Medications and GI System

8 terms by adelynns 

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Dicyclomine HCl (Bentyl)

Suppresses peristalsis and decreases gastric emptying

Opioid analgesics

Slow peristalsis and segmental contractions, often resulting in constipation

Anticholinergic drugs such as atropine or glycopyrrolate (Robinul)

Inhibit gastric acid secretion and depress gastrointestinal (GI) motility (Lehne, 2010) (Although useful in treating hyperactive bowel disorders, anticholinergics cause constipation.)

Antibiotics

Produce diarrhea by disrupting the normal bacterial flora in the GI tract (An increase in the use of fluoroquinolones in recent years has provided a selective advantage for the epidemic of Clostridium difficile)

Nonsteroidal antiinflammatory drugs

Cause GI irritation that increases the incidence of bleeding with serious consequences to older adults; rectal bleeding is often observed with GI irritation

Aspirin

Prostaglandin inhibitor; interferes with the formation and production of protective mucus and causes GI bleeding

Histamine2 (H2) antagonists

Suppress the secretion of hydrochloric acid and interfere with the digestion of some foods

Iron

Causes discoloration of the stool (black), nausea, vomiting, constipation (diarrhea is less commonly reported), and abdominal cramps

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