| Term | Definition |
|---|
| toxin: acetaminophen | antidote: N-acetylcysteine |
| toxin: acid/alkali ingestion | tx: upper endoscopy to evaluate for stricture |
| toxin: anticholinesterases, organophosphates | antidote: atropine, pralidoxime (reactivates cholinesterase) |
| toxin: antimuscarinic/ anticholinergic agents | antidote: physostigmine (anticholinesterase) |
| toxin: arsenic, mercury, gold | antidote: succimer, dimercaprol |
| toxin: BB | antidote: glucagon |
| toxin: barbiturates (phenobarbital) | antidote: urine alkalinization, dialysis, activated charcoal |
| toxin: benzodiazepines | antidote: flumazenil (antagonizes benzodiazepine receptors) |
| toxin: black widow bite | antidote: calcium gluconate, methocarbamol (Robaxin (R) centrally acting muscle relaxant) |
| toxin: carbon monoxide | 100% O2; hyperbaric O2 |
| toxin: copper, arsenic, lead, gold | antidote: penicillamine (chelates heavy metals) |
| toxin: cyanide | antidote: amyl nitrate, sodium nitrate (nitrates promote metHb formation --> conversion of cyanide to cyanmetHb); sodium thiosulfate (facilitates conversion of cyanide to thiocyanate) |
| toxin: digitalis | antidote: stop dig, normalize K+, lidocaine (for torsades), digibind |
| toxin: heparin | antidote: protamine sulfate |
| toxin: iron salts | antidote: deferoxamine |
| toxin: INH | antidote: pyridoxine |
| toxin: lead | antidote: succimer, CaEDTA, dimercaprol |
| toxin: methanol, ethylene glycol | antidote: etoh, fomepizole, dialysis, calcium gluconate (for ethylene glycol) |
| toxin: methemoglobin | antidote: methylene blue (accelerates reduction of metHb to Hb) |
| toxin: opioids | antidote: naloxone (opioid antagonist) |
| toxin: PCP | antidote: NG suction |
| toxin: salicylates | antidote: urine alkalinization, dialysis, activated charcoal |
| toxin: TCAs | antidote: sodium bicarbonate for QRS prolongation, diazepam or lorazepam for seizures, cardiac monitor for arrhythmias |
| toxin: theophylline | antidote: activated charcoal (consider repeat doses) |
| toxin: tPA, streptokinase | antidote: aminocaproic acid (inhibits plasminogen activators, interfering with fibrinolysis) |
| toxin: warfarin | antidote: vitamin K, FFP |
| MOA of black widow bite | neurotoxin acts at nerve endings to prevent relaxation of muscles, resulting in tetany (painful muscle contractions) |
Combine with other sets
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