← Gastrointestinal - microbiology #7 Export Options Alphabetize Word-Def Delimiter Tab Comma Custom Def-Word Delimiter New Line Semicolon Custom Data Copy and paste the text below. It is read-only. Select All Virus found in gut - group A? associated with gastroenteritis all are RNA virus (except adenovirus - dsDNA) mostly are naked http://o.quizlet.com/i/rKz9wry-ReFjfaRU08m_fQ.jpg virus found in gut - group B? found in gut, but don't cause gastroenteritis use GIT as stations to CNS http://o.quizlet.com/i/GJCIxK6mb-0ZfYAJoQ5NLg.jpg virus found in gut - group C? cause opportunistic infection, not related to GIT CMV, HSV, VZV, HIV http://o.quizlet.com/i/u5bKL8qPaudjzaKRk51HUQ.jpg examples of group A viruses? rotavirus adenovirus ("enteric" serotypes) calicivirus astrovirus "candidate" virus http://o.quizlet.com/i/2y7s2ZsJB3uZXXxvxUFFSw.jpg examples of group B viruses? polio, coxsakie A and B, echo, enterovirus, HAV etc diarrhoeal viruses - ssRNA? calicivirus astrovirus diarrhoeal viruses - dsRNA? rotavirus diarrhoeal viruses - dsDNA? adenoviruses shape of rotavirus? double-shelled capsid shape of calicivirus? round http://o.quizlet.com/i/thlDziTJlW2DRXE0xkM8ow.jpg shape of astrovirus? star-shaped http://o.quizlet.com/i/EIZ1vwp61vWIGEu-WOnUig.jpg shape of adenovirus? icosahedral? http://o.quizlet.com/i/oiKlll7YWQ_pKtIL7r8F0g.jpg small intestine - site of infection for? astrovirus adenovirus duodenum, jejunum - site of infection for? rotavirus jejunum - site of infection for ? calicivirus rotavirus - mostly during winter or summer? winter! rotavirus - mostly infect? infants <2 years old http://o.quizlet.com/i/nS1SIbJeVSaZL0DLJhWluQ.jpg calicivirus - mostly infect? older children and adults astrovirus and adenovirus - mostly infect? infants and children method of transmission for diarrhoeal viruses? fecal-oral route incubation period for rotavirus? 1-3 days (short) incubation period for calicivirus 0.5 -2 days (shorter than rotavirus) incubation period for astrovirus maybe 1-2 days incubation period for adenovirus 8-10 family for Rotavirus? Reoviridae family for Calicivirus? Caliciviridae what are VP4 and VP7? proteins of outer capsid for rotavirus (i.e. attachment proteins) http://o.quizlet.com/i/RvdVRxmfUZT_8vRrxrgauw.jpg why rotavirus is called "rota"? resembles a wheel attached by short spokes to the inner capsid an dcore http://o.quizlet.com/i/hZsu4FMCviIOesEriolcHA.jpg manifestions of rotavirus infections? >> vomiting, abdominal pain, low-grade fever >> water stools = no mucus, blood or pus How rotaviruses act at duodenum and jejunum? destroy villi --> decrease absorptive surface *gastric & colonic mucosa are unaffected gastric time emptying greatly delayed decrease production of brush border enzymes nonstructural protein NSP4 of rotavirus? behave as enterotoxin (like LT toxin of E.coli and cholera toxin) --> cause diarrhoea what is Hakuri? clear stool --> caused by rotavirus http://o.quizlet.com/i/6G6ZDvPPLVa2oMTipCFb6g.jpg major complications of rotavirus? >> severe dehydration >> hypernatremia infectivity of rotavirus? highly infectious --> spreads quickly 2 genera of caliciviridae that cause diarrhoea? >> "norwalk-like" virus (sometimes referred as Noroviruses) >> "Sapporo-like" viruses calicivirus - extremely hard? Yes! Infectivity persists after exposure to acid, ether and heat (60 centigrade for 30 mins) http://o.quizlet.com/i/Xyi1IaW_cLOmde3hgWN3WA.jpg How to get infected by calicivirus? consume contaminated water, uncooked shellfish and other foods http://o.quizlet.com/i/bWbsn5vkta1jxR5v8lv5SA.jpg Adenovirus that cause viral gastroenteritis in young children? serotypes 40, 41 and perhaps 38 http://o.quizlet.com/i/JpLMHBlnfZ4gDVBA_Pd-fg.jpg astrovirus causes? often mild gastroenteritis antibodies for astrovirus? most people have antibody against astrovirus by the age of 3years old corona virus - DNA or RNA? RNA http://o.quizlet.com/i/X3sOipqq5zKAeG9oIcDuuw.jpg examples small round viruses? >> parvovirus >> enterovirus >> cubic bacteriophages