NAME: ________________________

← Oncology Test

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Oncology

5 Written Questions

5 Matching Questions

  1. Antiandrogens
  2. Camptothecins
  3. Vinca alkaloids
  4. Imatinib
  5. Antiestrogens
  1. a Bind to estrogen receptors on tumor surface to prevent cell growth/cause cell death
  2. b Inhibit the binding of testosterone to the androgen receptors in the prostate
  3. c G2 & M phase

    Antimicrotubular agent as above
  4. d S-Phase

    Topoisomerase I inhibitor (causing DNA breakage)
  5. e Gleevec

    Tyrosine kinase inhibitor

5 Multiple Choice Questions

  1. S-Phase

    Similar to normal cell substances & when incorporated in cell, makes cell unable to divide
  2. G2 & M Phase

    Antimicrotubular agent, inhibits mitosis by interfering with the microtubules, which help move chromosomes during mitosis
  3. Adriamycin

    Anthracycline
  4. * Amnestic, anxiolytic, sedative, Great for anticipatory vomiting
    * Sedation, hypotension, disinhibition, motor incoordination
    * Lorazepam
  5. Hycamtin

    Camptothecins

5 True/False Questions

  1. Alkylating Agent → Non-Specific

    Alkylation of DNA

          

  2. Trastuzumab → Herceptin

    Monoclonal Antibody

          

  3. Leuprolide → Femara

    Aromatase Inhibitor

          

  4. Antitumor Abx (Anthracycline) → S-Phase

    Similar to normal cell substances & when incorporated in cell, makes cell unable to divide

          

  5. Monoclonal Antibodies → Target specific antigens on cancer cell surface. Marks cell for attack by immune system. Blocks specific receptors. Some deliver antitumor agent to a target.