ch 14

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Created by:

kfuntanilla  on December 9, 2010

Subjects:

bio 311d

Description:

mendelian genetics, sex linkage

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ch 14

trait
Any detectable variation in a genetic character
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Terms

Definitions

trait Any detectable variation in a genetic character
monohybrid cross An organism that is heterozygous with respect to a single gene of interest. all the offspring from a cross between parents homozgous for different alleles are monohybrids. For example, parents of genotypes AA and aa produce a genotype of Aa.
dihybrid cross an organism that is heterozygous with respect to two genes of interest. All the offspring from a cross between parents doubly homozygous for different alleles are dihybrids. For example, parents of genotypes AABB and aabb produce a dihybrid of genotype AaBb.
phenotype The physical traits that appear in an individual as a result of its gentic make up.
genotype an organism's genetic makeup, or allele combinations
law of segregation Mendel's first law, stating that each allele in a pair separates into a different gamete during gamete formation.
law of independent assortment Mendel's second law, stating that each allele pair segregates independently during gamete formation; applies when genes for two characteristics are located on different pairs of homologous chromosomes.
incomplete dominance The situation in which the phenotype of heterozygotes is intermediate between the phenotypes of individuals homozygous for either allele.
polygenetic inheritance additive effect on two or more genes on a single phenotypic characteristic
pleiotropy The ability of a single gene to have multiple effects.
cystic fibrosis a human genetic disorder caused by a recessive allele for a chloride channel protein; characterized by an excessive secretion of mucus and consquent vulnerability to infection; fatal if untreated (4% whites are carriers - most common lethal genetic disease)
sickle-cell disease a human genetic disease caused by a recessive allele that results in the substitution of a single amino acid in a globin polypeptide that is a part of the hemoglobin protein; characterized by deformed red blood cells (due to protein aggregation) that can lead to numerous symptoms
achondroplasia A form of human dwarfism caused by a single dominant allele; the homozygous condition is lethal
huntington disorder A genetic disease caused by a dominant allele causing degeneration of the nervous system. Usually fatal 10-20 yrs after the onset of symptoms

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