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Hep A

travel problem. IgM spikes acute, IgG shows immunity

HepE

lethal in 20% of pregancy cases

HepB virion

ssDNA and dsDNA+RT+DNApol+RNAHseH

HepB profile

youth-> chronic disease, age->acute disease. 4-12wk incubation

Chronic HepB

HBsAg and anti-HBcAgIgG

Acute HepB

HBeAg, HBsAg, anti-HBcAgIgM

Immunized

anti-HBsAg

HepC profile

causes HCC 10-12yrs post infection, IV DRUG USERS not treated b/c psychiatric instability, flavivirus (+RNA)

HepC Dx

EIA-ELISA+ > RIBA/RTPCR+ > increased ALT

HDV

co HepB leads to superinfection in Middle East, Africa, and S. Italy

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