| Term | Definition |
|---|
| PAF (platelet activating factor) | Acetyl group instead of fatty acyl at C2 of glycerol backbone. Relatively water soluble. |
| sphingosine | derived from palmityl-coA and serine |
| condensation, reduction, oxidation | Steps in formation of sphingosine |
| NADPH2 | sphingosine synthesis reducing agent |
| FAD+ | sphingosine synthesis oxidating agent |
| CDP | carrier in phosphoglyceride formation |
| cytidine diphosphate | CDP = |
| ganglioside | branched oligosaccharide WITH N-acetyl neuraminic acid (sialic acid) |
| globoside | branched oligosaccharide W/O sialic acid |
| ceramide | N-Acyl-sphingosine a.k.a. |
| hexosaminidase A (beta-n-acetylhexosaminidase) | enzyme deficient in Tay-Sachs Disease |
| beta-glucosidase (glucocerebrosidase) | enzyme deficient in Gaucher's Diseaes type 1 |
| sphingomyelinase | enzyme deficient in Niemann-Pick disease |
| phospholipase A1 | cleaves acyl/fatty acid at C1 in phospholipids |
| phospholipase A2 | cleaves acyl/fatty acid at C2 in phospholipids |
| phospholipase C | cleaves P-alcohol (inositol in in DAG) from C3 in phospholipids |
| phospholipase D | cleaves alcohol only from C3 in phospolipids |
| phospholipase C | activated by G-protiens, hormonally regulated |
| phospholipase A2 | stimulated by hormones, cytokines, thrombin |
| thromboxanes | found in platelets, +vasoconstriction, + blood clots, + platelet aggregation |
| cyclooxygenase | Target of anti-inflammatory drugs, a.k.a. COX |
Combine with other sets
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