pharmaco review GEO
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Created by:
german1969 on January 27, 2011
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45 terms
Terms | Definitions |
|---|---|
 Drug of choice for bacterial meningitis? | Ceftriaxone or cefotaxime |
| What is almost solely employed in tx of Tuberculosis as 2nd LINE AGENT ONLY | Cycloserine orally |
| Drug that treats Endocarditis bacterial infections? (no prophy) | Vancomycin is given slowly through IV to treat Endocarditis |
| Drug that treats mixed infections? more than one infections | more than one infection is usually treated with more than one drug. |
| What is resistant to staphylococcal beta lactamases | oxacillin |
| Betalactam groups | ... |
| Which are synergistic | -aminoglycoside + B lactam or -vancomycin Sulfonamides + trimethoprim/pyrimethamine |
| Which are inhibition of cell wall synthesis | All B-lactams, peptides, carbapenems, monobactams, bacitracin, vancomycin, fosfomycin, cycloserine |
| Standard Penicillins are the ones with ___ | letters (V & G) |
| Which are the G+'ve's | Strep, Staph, Enterococcus, Clostridium, actinomyces, bacillus, cornybacterium, lactobacillus, listeria, mycobacterium, nocardia,, propionibacterium, anything -coccus |
| What is greatest against G +'ve and little G-'ve and inactivated by B-lactamase or penicilinases | Peni G |
| What are comparable to peni G but have improved G-'ve permeability | extended spectrum penicillins |
| These have inc activity against which G-ve microorganisms | Proteus, E. coli, H. influenza, moraxella |
| The above are called __ which mean they improve G-'ve (bacilli/cocci) permeability | aminopenicillins |
| Classify each PEPTIDES as G+ve, G-ve or combo | NEXT...... ;) |
| Only G+ve | Bacitracin, Gramicidin, Vancomycin, Datomycin |
| Only G-ve | Polymyxin B |
| Both -ve and +ve | Fosfomycin, Cycloserine |
| Most important thing for 3rd generation is that they __ | cross the BBB |
| Most important thing for 3rd generation is that they cross the BBB and are used for | bacterial meningitis |
| in order to treat meningitis, the drug must | cross the BBB |
| Which 2 are the 1st line agents for bacterial meningitis due to H influenzae | ceftriaxone & cefotaxime |
| Which is the 1st line agent for tx of Neisseria gonorrhoeae | ceftriaxone |
| Which 2 are the 1st line agent for infections due to penicillin resistant streptococcus pneumonia | ceftriaxone & cefotaxime |
| Which is 1st line agent for infection due to pseudomonas aeruginosa | ceftazidime |
| Which is the most widely prescribed 3rd generation cephalosporin | cefdinir |
| Which is used for skin & soft tissue infections (staph aureus & strep pyogenes) | cefdinir |
| What are 1st line of drugs for N gonorrhea | ceftriaxone & cefixime |
| Which is 1st line agent for tx of Neisseria gonorrhoeae in ORAL form | cefixime |
| Which is 1st line agent for tx of Neisseria gonorrhoeae in IV or IM form (not given orally) | ceftriaxone |
| What is the 4th generation cephalosporin | cefepime |
| Vanco is __ line agent for penicillin resistant streptococcus pneumoniae | 1st |
| 1st line agent for penicillin resistant streptococcus pneumoniae | Vanco |
| Vanco it's restricted to tx of | severe G+'ve infections |
| All cephalosporins are active against G+'ve cocci/bacilli including | staph and strep |
| Treat staph and strep | All cephalosporins are active against G+'ve cocci/bacilli including |
| Polymyxin is useful against g-ve rods including __ | pseudomonas |
| Treat pseudomonas | Polymyxin |
| __ is used to treat tuberculosis, plague and tularemia | streptomycin |
| Which is also for chancroid, cholera, plaque, anthrax and tularemia | cipro Note: Anthrax is the only G+ve above treats |
| Can use __ for actinomycosis (abcess), syphilis, tetanus, anthrax, meningitis, bacterimia | peni G |
| Fluoros tx __ but not __ | gonorrhea; syphilis |
| The cephamycins (subclass of 2nd generation) which are cefoxitin & cefotetan are similar to 2nd generation agents except they have better ___ | anaerobic activity |
| the anterior are very active against which anaerobes? | B fragilis & C perfringens |
| which is 1st line agent for bacteroides | cefoxitin |
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