Blood Cancers buzzzzzzz

Created by kvandrunen 

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JAK2 mutation

polycythemia vera, essential thrombocytosis

t(14;18) bcl-2 gets translocated to Ig locus

follicular lymphoma

smudge cells

CLL/SLL

TRAP

hairy cell leukemia

cyclin D1 gene overexpression

mantle cell lymphoma

follicular lymphoma transforms to this

Diffuse Large B Cell Lymphoma

auer rod

AML

gingiva infiltration

AML

asymptomatic M-spike

MGUS

TDT positive

ALL

skin lesion variant

Acute T-Cell Leukemia Lymphoma

Birbeck granules

langerhans cell histocytosis

Philadelphia Chromosome

CML. (t9;22) BRC-ABL

imatinib

CML.

punched out bone lesions, osteoporosis

Multiple Myeloma

CRAB organ damage

Multiple Myeloma - hypercalcimia, renal insufficiency, anemia, bone lesions

teardrop cells

primary myelofibrosis (aka chronic idiopathic myelofibrosis)

ALK gene rearrangements

Anaplastic Large Cell Lymphoma

horseshoe nuclei

Anaplastic Large Cell Lymphoma

middle ground between MGUS and Multiple Myeloma

Smouldering Myeloma

c-myc translocated to Ig locus (t8;14)

Burkitts

starry sky

Burkitts

chronic gut inflammation

marginal zone lymphoma

abnormally large and weird platelets

Essential Thrombocytosis

anti-CD20 antibody therapy works

follicular lymphoma

tons of small lymphocytes, few RS

lymphocyte rich classical Hodgkins

RS cells and varients on a mixed cellular background

mixed cellularity classical Hodgkins

few lymphocytes and lots of RS cells

lymphocyte depleted classical Hodgkins

fibrous nodular pattern + lacunar cells

nodular sclerosis classical Hodgkins

popcorn cells, nodularity, lymphocytes

Nodular lymphocyte predominant Hodgkin lymphoma

centrocytes and centroblasts

follicular lymphoma

lymphoid lineage

T Cells, B Cells(and plasma), natural killer cells

myeloid lineage

RBCs, monocytes, neutrophils, basophils, eosinophils, megacaryocytes

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