Ch 6 Lymphatic and Immune Systems
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nikitha123 on February 2, 2011
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121 terms
Terms | Definitions |
|---|---|
allergist | specializes in diagnosing and treating conditions of altered immunologic reactivity |
hematologist | specializes in diagnosing and treating diseases and disorders or the blood and blood-forming tissues |
immunologist | specializes in diagnosing and treating disorders of the immune system |
oncologist | specializes in diagnosing and treating malignant disorders such as tumors and cancer |
interstitial fluid | plasma that flows out of capillaries into the spaces between the cells |
lymph | remaining interstitial fluid that has not been reabsorbed |
lymph capillaries | microscopis thin-walled tubes located just under the skin, carry lymph from the tissues to the deeper and larger lymphatic vessels and ducts |
right lymphatic duct | right side of head and neck; upper right quadrant of body |
thoracic duct | all other areas of the body drain into it |
lacteals | specialized lymph capillaries located in the villi that line the walls of the small intestine; fats and fat soluble vitamins absorbed |
lymph nodes | small bean shaped structures located in lymph vessels; filter harmful substances such as bacteria, viruses, and malignant cells |
tonsils | masses of lymphatic tissue that form a protective ring around the nose and upper throat |
adenoids | nasopharyngeal tonsils; located in the nasopharynx |
palantine tonsils | located in the right and left sides of the portion of the throat that is visible through the throat |
lingual tonsils | located at the base of the tongue |
vermiform appendix | lymphatic tissue that hands from the lower portion of the cecum of the large intestine; protects against the entry of invaders through the digestive system |
Peyer's patches | small bundles of lymphatic tissue located on the walls of the ileum (final portion of the small intestine) |
spleen | saclike mass of lymphatic tissue located in the left upper quadrant of the abdomen, just inferior the diaphragm and posterior to the stomach |
hemolytic | destroys worn out blood cells and liberates hemoglobin; spleen |
cervical lymph nodes | in the neck |
axillary lymph nodes | under the arms |
inguinal lymph nodes | in the groin area of the lower abdomen |
thymus | located superior to the heart and composed of lymphatic tissue |
lymphadenitis | swollen glands; inflammation of the lymph nodes |
lymphadenopathy | any disease process usually involving the enlargement of the lymph nodes |
persistent generalized lymphadenopathy | PGL; continued presence of enlarged lymph nodes; indication of the presence of a malignancy or a deficiency in immune system function |
lymphangioma | congential malformation of the lymphatic system, is a benign tumor formed by an abnormal collection of lymphatic vessels |
splenomegaly | abnormal enlargement of the spleen; may be due to bleeding caused by an injury, infectious disease like mononucleosis, or abnormal functioning of the immune system |
splenorrhagia | bleeding from the spleen |
lymphangiography | radiographic examination of the lymphatic vessels after the injection of a contrast medium |
lymphedema | swelling due to an abnormal accumulation of lymph within the tissues |
primary lymphedema | hereditary disorder that may appear at any time in life and most commonly affects the legs |
secondary lymphedema | caused by cancer treatment (lymph node removal, chemotherapy, and/or radiation therapy), burns or trauma; affects the limb or body area nearest the missing lymph nodes |
first line of defense | intact skin, respiratory system, digestive system, lymphatic system |
immune reaction | one way in which the immune system destroys pathogens that have entered the body |
antigen | any susbstance the body recognizes as foreign |
antibody | disease-fighting protein created by the immune system in response to the presence of a specific antigen |
lymphocytes | white blood cells formed by the bone marrow that specializes to act as antibodies so they can attack specific antigens |
B cells/ B lymphocytes | specialized lymphocytes that produce and secrete antibodies; tranaformed into a plasma cells when it reaches an antigen it has been coded to destory |
T cells | T lymphocytes; small lymphocytes that have matured in the thymus as a result of their exposure to thymosin |
interferon | produced by T cells, family of proteins whose specialty is fighting viruses by slowing or stopping their multiplication |
lymphokines | produced by T cells; direct immune response by signaling between cells of the immune system; attract macrophages to infected area |
macrophage | eats invading cells and interacting with other cells of the immune system |
phagocyte | large white cell that can eat and destroy substances such as cell debris, dust, pollen, and pathogens |
immunoglobulins | secreted by B cells; known as antibodies; five major classes are IgA, IgD, IgE, IgG, and IgM |
complement | series of more than 25 complex proteins that normally circulate in the blood in an inactive form; activated by contact with antigen; puncture antigen's cell membrane once activated |
immunity | state fo being resistant to a specific disease |
natural immunity | passed from mother to developing child before birth; additional immunity provided by breast milk |
acquired immunity | active immunity; obtained by developing antibodies during an attack of infectious disease |
artificial immunity | acquired immunity; obtained through immunication or vaccination |
allergy | hypersensitivity; overrreaction of the body to a specific antigen |
cellular response | localized/ delayed allergic response; body does to react first time it is exposed to the allergen; sensitivity established after future contacts |
systemic reaction | anaphylaxis; severe response; swelling and blockage of airways; can quickly become fatal |
scratch test | diagnostic test to identify commonly troublesome allergens |
autoimmune disorder | immune system reacts incorrectly to normal antigens and creates antibodies against the body's own tissues |
immunodeficiency disorder | one or more parts of the immune systemare missing or not working properly |
human immunodeficiency virus | bloodborne pathogen that progressively damages or kills cells of the immune system |
acquired immunodeficiency syndrome | advanced stage of HIV infection |
ELISA | enzyme-linked immunosorbent assay; blood test used to screen for the presence of HIV antibodies; can produce a false-positive |
Western blot | test given to confirm ELISA positive findings |
immunotherapy | treatment of disease that involves either stimulating or repressing the immune system |
rheumatoid arthritis | skeletal system |
myasthenia gravis | muscular system |
pernicious anemia | cardiovascular system |
Crohn's disease | digestive system |
multiple sclerosis | nervous system |
alopecia areata | integumentary system |
lupus erythematosus | integumentary system |
scleroderma | integumentary system |
vitiligo | integumentary system |
Type 1 diabetes mellitus | endocrine system |
Grave's disease | endocrine system |
Hashimoto's thyroiditis | endocrine system |
synthetic immunoglobulins | immune serum; used as a postexposure preventative measure (rabies and some hepatitis) |
synthetic interferon | treatment of multiple sclerosis, hepatitis C, and some cancers |
monoclonal antibodies | may enhance a patient's immune response to the cancer |
immunosuppression | treatment used to interfere with the ability of the immune system to respond to stimulation by antigens |
corticosteroid drug | hormone-like preparation used primarily as an anti-inflammatory and as an immunosuppressant |
cytotoxic drug | kills or damages cells; used as immunosuppressants and as antineoplastics |
pathogen | microorganism that causes disease |
bacteria | group of one-celled microscopic organisms |
bacilli | rod shaped spore forming bacteria; tetanus and tuberculosis |
rickettsia | small bacterium that lives in lice, fleas, ticks, and mites; Rocky Mountain spotted fever |
spirochetes | spiral shaped bacteria that have flexible walls and are capable of movement; Lyme disease |
staphylococci | bacteria that form irregular groups or clusters; pus-forming infections such as boils and furuncles |
streptococci | bacteria that form a chain; severe pharyngitis (strep throat) |
fungus | simple parasitic plant |
viruses | very small infectious agents that live only by invading cells |
cytomegalovirus | group of large herpes type viruses that cause a variety of diseases |
infectious mononucleosis | caused by Epstein-Barr virus; fever, sore throat, and enlarged lymph nodes |
measles | acute, highly contagious infection caused by rubeola virus and transmitted airborne |
mumps | acute viral disease characterized by the swelling of the parotid glands |
rabies | acute viral infection that may be transmitted to humans by blood, tissue, or saliva of an infected animal |
rubella | German measles (3 day measles); viral infection characterized by fever and a diffuse, fine, red rash |
varicella | chicken pox; caused by herpes Varicella zoster |
herpes zoster | shingles; acute viral infection characterized by painful skin eruptions that follow the underlying route of the inflamed nerve |
West Nile virus | causes flu like symptoms; carried by birds and transmitted to humans by mosquito or tick bites |
antibiotics | chemical substances capable of inhibiting growth or killing pathogenic microorganisms |
-cide | kills |
-static | slows or stops growth of |
neoplasm | tumor; new and abnormal tissue formation |
angiogenesis | process by which a tumor supports it growth by creating its own blood supply |
antiangiogenesis | form of cancer treatment that disrupts this blood supply to the tumor |
benign | non-life threatening |
staging | process of classifying tumors with respect to how far the disease has progressed, the potential for its responding to therapy, and the patient's prognosis |
carcinoma | malignant tumor that occurs in epithelial tissue |
adenocarcinoma | any one of a large group of carcinomas derived from glandular tissue |
sarcoma | malignant tumor that arises from connective tissue |
osteosarcoma | malignant tumor ususally of the upper shafts of long bones |
myosarcoma | malignant tumor derived from muscle tissue |
Kaposi's sarcoma | may affect skin, mucous membranes, lymph nodes, and internal organs; associated with HIV |
lymphoma | general term applied to malignancies that develop in the lymphatic system |
Hodgkin's lymphoma | distinguished by presence of Reed-Sternberg cells (large cancerous lymphocytes); stages I to IV |
non-Hodgkin's lymphoma | all lymphomas not Hodgkin's; low-grade (slow)-->intermediate-grade (growing moderately)-->high-grade (growing rapidly) |
invasive ductal carcinoma | infiltrating ductal carcinoma; starts in the milk duct and breaks through the wall of the duct to invade fatty breast tissue; most common |
ductal carcinoma in situ | breast cancer at its earlist stage (stage 0) before cancer has broken through the wallof the milk duct; cure rate near 100% |
invasive lobular carcinoma | infiltrating lobular carcinoma; starts in milk glands, breaks through walls and invades fatty tissue |
sentinel node | first lymph node to come in contact with cancer cells |
modified radial mastectomy | surgical removal of the entire breast and axillary lymph node |
brachytherapy | use of radioactive materals in contact with, or implanted into, the tissues to be treated |
teletherapy | radiation therapy administered at a distance from the body |
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