endochondral ossification
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Created by:
icedrosebud on October 5, 2008
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Description:
describe steps in endochondral ossification
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19 terms
Terms | Definitions |
|---|---|
 endochondral ossification | bones replaces existing cartilage |
| unborn child | bones such as humerus and femur are completely made of hyaline cartilage |
| cartilage model | forms shape of bone--long bone |
| cartilage model | formed by chondroblasts |
| cartilage model | perichondrium forms around model |
| growth of cartilage model | chondroblasts get buried in matrix and develop into chondrocytes |
| growth of cartilage model | chondrocytes repoduce and continue secreting cartilage |
| growth of cartilage model | center of model begins to clacify- causes chain reaction to cell death because nutrients can't travel through calcified areas |
| primary ossification center | ossification starts from the external surface--invades the middle of the bone |
| primary ossification center | artery penetrates the perichondrium- causes osteogenic cells to differentiate into osteoblasts |
| primary ossification center | osteoblasts begin to secrete compact bone tissue |
| primary ossification center | more blood vessels invade the inner portion of calcified cartilage |
| primary ossification center | stimulate formation of the primary ossification center--bone tissue replaces cartilage |
| medullary cavity | primary ossification center expands toward the ends of the bone |
| medullary cavity | osteoclasts break down existing bone in the middle to form the cavity |
| secondary ossification center | blood vessels invade the ends of the bones |
| secondary ossification centers | process is the same as primary centers, but no medullary cavity formed |
| formation of articular cartilage and epiphyseal plate | cartilage on the epiphyseal remains and is the articular cartilage |
| formation of articular cartilage and epiphseal plate | cartilage between epiphysis and diaphysis remains as the epiphyseal plate (growth plate) |
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