Precursor of PDH
Def: Beri Beri, Wernwicke's Encephalopathy
Precursor of FADH
Precursor of NADP and NAD
Pentothenic Acid (B5)
Precursor for CoA
coenzyme in amino acid metabolism
Precursor in carboxylases
Folic Acid (B9)
Def: Megaloblastic Anemia
Deficiency: Osteomalacia, rickets
Excess: Tissue calcification
Def: Vomiting, decreased plasma volume
Def: Cardiac arrythmias, vomitting
Excess: Cardioplegia, renal failure
B-Carotene important antioxidant
Found in plants
Retinoic acid regulates growth of cells (acne treatment)
Toxic: Hypervitaminosis A, congenital defects
Calcium homeostasis: Increase calcium in blood,
increase bone resorption,
increase calcium absorption from intestine,
increase calcium reabsorption from kiney
Free radical scavenger protects vit E and A
Coenzyme in hydroxylation reactions- collagen synthesis
Keeps Fe2+ reduced in gut allowing iron absorption
Carboxyglutamate and calcium bridges
glutamate to carboxyglutamate
Water Soluble Vitamins
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