2-2. Spinal Cord & Structures

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Created by:

bmcs  on February 13, 2011

Subjects:

anatomy

Description:

Lab 2-Part 2

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2-2. Spinal Cord & Structures

vertebral column structure
-32 vertebral levels
-7 cervical, 12 thoracic, 5 lumbar, 5 fused sacral, 3-5 fused coccygeal vertebrae
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vertebral column structure -32 vertebral levels
-7 cervical, 12 thoracic, 5 lumbar, 5 fused sacral, 3-5 fused coccygeal vertebrae
vertebral level -each has muscles, skin, bones
-trunk=stack of coins
-each=segment
-neurons supply instruction to/from segments via spinal nerves
spinal nerves numbering -based on where it exits from vertebral canal and vertebral level
spinal segment each region on spinal cord that supplies a pair of spinal nerves
spinal cord length -shorter than vertebral canal
-most spinal segments are located more superiorly than associated pair of spinal neres exit
T10 vertebral level -L1 spinal segment located and exits
L1-L5 spinal segment is directly dorsal to T10-T12 (half)
S1-S5 spinal segment is directly dorsal to T12 (half)-L1 (half)
misalignment between spinal segment and vertebral level due to -result of differential growth
-fetal development-vertebral column elongates faster than spinal cord; column pulls and elongates lower spinal nerves
-lower spinal nerves forms bundle=cauda equina
cauda equina bundle of spinal nerves at L2-L5-S1
meninges -covers & protects the brain & spinal cord
dura mater -outermost & toughest layer
-in vertebral canal, surrounded by fatty cushion
epidural space -fatty cushion that surrounds spinal cord below dura mater
-site for anesthetic injection during labor
epineurium -extension of dura mater and surround spinal nerves
arachnoid mater -deep of the dura mater
-spongy looking meninges with subarachnoid space
pia mater -deepest meninges & directly meets with spinal cord
pia mater specialization -1-there are at least 20 pairs of lateral projections=denticulate ligaments
-2-filum terminale
denticulate ligaments -lateral projections
-anchor spinal cord to dura mater
-limit movement of spinal cord
filum terminale -at end of conus medularis
-pia mater continues as thin thread that anchors end of spinal cord to the sacrum
spinal cord parts -3
-white matter (outer region), grey matter, central canal
spinal cord white matter -myelinated axons
-oriented vertically to/from CNS
-grouped in 3 columns on each sagittal plane
spinal cord grey matter -3 columns: dorsal horn, ventral horn, lateral horn
lateral horn of spinal cord grey matter -only present at thoracic spinal levels
-contains sympathetic nervous system neurons
central canal of spinal cord center, cavity in continuity with ventricles in the brain
spinal cord is devoted to -either sending information up to the brain or
sending motor commands down to the appropriate level of the spinal cord
ascending pathways -systems of neurons that bring information to the brain
-signals travel along
3 neurons, considered 1st, 2nd, and 3rd order neurons
spinothalamic tract example of an ascending pathway
path of ascending pathway-neuron (1st order): it enters the dorsal horn where
sensory neurons synapse with interneurons
-the interneuron (2nd order): it decussates (crosses) to the contralateral (opposite) side and its axon enters the white matter. From here, the axon runs up to the thalamus where it synapses
-another interneron (3rd order): the axon is wired to
the appropriate part of the somatosensory cortex
descending pathways -systems of neurons that bring motor information
from the brain down to the appropriate spinal level
corticospinal tract -example of a descending pathway
primary motor cortex where voluntary motor commands originate from
descending path -upper motor neuron-
-this interneuron travels down the white
matter corticospinal tract
-decussation occurs in the medulla, and the
tract continues down the spinal cordmuscles
-at the appropriate spinal level, the axon
leaves the tract and enters the ventral horn
where it synapses with
upper motor neuron -pyramidal neuron
lower motor neuron -this is the motor neuron of the Peripheral Nervous System (PNS)
-it leaves the spinal cord to innervate skeletal musclesSynapse in ventral horn
spinal nerve forms from joining of dorsal & ventral roots
dorsal & ventral roots 2 major tributaries that form the spinal nerve
dorsal root -carries sensory infromation to the dorsal horn of the spinal cord
-has a large collection of cell bodies that form the dorsal root ganglion
-
pseudounipolar -sensory neurons are unique in having the
cell body in the middle of the course of the
axon
- such neurons are called unipolar
ventral root -neurons of the ventral root have their
cell bodies in the ventral and lateral horns
of the spinal cord
-the axons of the ventral root are entirely motor
somatic -outer body
-bones, skeletal mucles, skin
visceral -interior cavities of the body
-digestive, respiratory, cardiovascular systems
visceral and sensory Besides a simple division between sensory and motor, the nervous system is also distinguished on the basis of
4 functional components of gray matter of spinal cord ■ Somatic sensory: from skin, skeletal muscles, joints
■ Visceral sensory: from the viscera
■ Somatic motor: to skeletal muscles
■ Visceral motor: to smooth muscle and glands
rami= branches of spinal nerve from its roots
rami main branches dorsal ramus, ventral ramus, communicating rami
dorsal ramus carries somatic motor and somatic
sensory to the dorsal body wall
ventral ramus carries somatic motor and somatic
sensory to the lateral and anterior body wall
communicating rami -carry visceral motor (sympathetic) and visceral sensory neurons to and from the
viscera (heart, lungs, abdominal organs)
-distribute neurons via sympathetic chain
sympathetic chain -runs parallel to the spinal cord and sends branches towards the thoracic and abdominal cavities
ascending tracts -inform your brain of sensations and descending tracts give voluntary commands
-many sensory inputs elicit automatic motor responses (brain not involved in response to stimulus)
spinal reflexes -elicit automatic motor responses when the brain is not involved in the response to the stimulus
-these are involuntary circuits
simplest reflexes sensory neuron synapsing with a motor neuron
monosynaptic reflexes simplest of reflexes involving a snesory neuron synapsing with a motor neuron
monsynaptic reflex path -stimulus-sensory neuron in spinal cord-sends axon terminal to ventral horn-motor neurons stimulated
monosynaptic reflex example stretch reflex
stretch reflex -stretch of the muscle reflexively causes contraction of the same muscle leading to greater stability of joints
-the patellar (or knee-jerk) reflex is one example of a stretch reflex
stretch reflex example -the patellar (or knee-jerk) reflex
awareness of reflex -the sensory neuron also sends a projection upward along an ascending tract in order to inform the brain of the sensation. Although the brain is not participating in the reflex, it is nonetheless aware of the stimulus
stimulus path of stretch reflex 1. Stimulation of stretch receptor
2. Signal occurs along sensory neuron
3. Synapse with motor neuron
4. Signal occurs along motor neuron
polysynaptic reflexes -many reflexes involve one or several interneurons
withdrawal reflex -example of polysynaptic reflex
-protective in nature.
stepping on nail -withdrawal reflex
-immediate response of your foot is to withdraw
-the stimulus travels along a sensory neuron, and in the spinal cord synapses with one or several interneurons
synapsing allows -signal to diverge to multiple locations
divergence of signal-ex: motor neurons are stimulated in hip, thigh, & lower lege
-inhibitor signals may be sent to muscles that oppose withdrawal
-In some reflexes, signals are sent to the
contralateral side of the body, ensuring that you
withdraw one foot from the source of pain and stabilize the other leg to remain standing
-there are hundreds of such reflexes wired into your spinal cord, all functioning without direction from the brain
pathway of nail stimuli 1. Stimulation of pain receptor
2. Signal occurs along sensory neuron
3. Synapse with interneuron(s)
4. Signal occurs along motor neuron
5. Muscle is stimulated to contract,
withdrawing limb from pain
draw:
􏰁A motor neuron to a back muscle
􏰁A motor neuron to your six pack abs
􏰁A motor neuron to your stomach
􏰁A sensory neuron from the skin of your back
􏰁A sensory neuron that tells you that you're full
􏰁A sensory neuron from your belly button
...

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