Ch 5 The Structure and Function of Large Biological Molecules

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joviandudley  on February 24, 2011

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biology

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Holloman Group

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Ch 5 The Structure and Function of Large Biological Molecules

macromolecules
large molecules composed of thousands of covalently connected atoms
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macromolecules large molecules composed of thousands of covalently connected atoms
polymer A long molecule consisting of many similar building blocks
monomers building blocks of polymers
condensation reaction when two monomers are combined covalently through the removal of the equivalent of a water molecule
dehydration reaction when two monomers are combined covalently through the removal of the equivalent of a water molecule
enzymes a protein acts as catalyst to speed up the dehydration or condensation reaction
hydrosis a reaction that reverses the dehydration or condensation reaction by disassembling polymers to monomers
carbohydrates sugars and polymers of sugars
monosaccharides formula multiples of CHâ‚‚0
serve as a major fuel for cells and as raw material for building molecules What is the main purpose of a monosaccharides?
disaccharide formed when a dehydration reaction joins two monosaccharides
glycosidic linkage a covalent bond associated with sugar
glycosidic bond a covalent bond associated with sugar
polysaccharides the polymers of sugars that have storage and structural roles
starch storage polysaccharide in plants consists entirely of glucose monomers
glycogen is a storage polysaccharides in animals that consists of glucose
celloulose the principle component of the plant cell wall
alpha glucose has helical sttructure
beta glucose has a straight structure
chitin a structuctural polysaccharide found in the exoskeleton of antropods
lipids the one class of large biological molecules that do not form polymers
glycerol+fatty acids = ? fats
fatty acid carboxyl group attached to a long carbon skeleton
triacylglycerol Three fatty acids linked to one glycerol molecule
triglyceride biology term used for triacylglycerol
saturated fatty acids have the max number of hydrogen atoms possible and no double bonds
unsaturated fatty acids have on or more double bond
hydrogenation the process of converting unsaturated fats to saturated fats by adding hydrogen
trans fats made when hydrogen is added to the fat molecules in vegetable oils
phospholipid 2 fatty acids and a phosphate group attached by glycerol
steroids lipids characterized by a carbon skeleton consisting of four fused rings
cholesterol an important steroid that is a component in animal cell membranes
enzymes macromolecules that speed up the dehydration process
polypetides polymers built from the same set of 20 amino acids
protein consists of one or more polypeptides twisted, folded, and coiled into a unique shape
amino acids organic molecules with carboxyl and amino groups
peptide bonds links amino acids together
primary structure of a protein sequence of amino acids
secondary structure of a protein coils and folds in the polypeptide chain
Primary structure is determined by inherited _____________ genetic information
pleated sheet The folded arrangement of a polypeptide in a protein's secondary structure.
tertiary structure determined by interactions among various side chains (R groups)
Van der Waals interaction contribute in _________ proteins. tertiary structure
van der Waals interaction a weak electrical attraction between two hydrophobic side chains
disulfide bridges Strong covalent bonds that reinforce the protein's structure
quatermary structure two or more polypeptide chains form one macromolecule
denatured protein loss of a protein's native structure
chapernonins protein molecules that assist the proper folding of other proteins
gene made of the nucleic acid DNA
deoxyribonucleic acid DNA
ribonucliec acid RNA
polynucleotides Nucleic acids polymers linked together
nucleotides polynucleotides made of monomers
pyrimidines nitrogenous base with a single six-membered ring
purines nitrogenous base with a six-membered ring fused to a five-membered ring
deoxyribose a five carbon sugar in DNA
ribose a five carbon sugar in RNA
carbohydrates macromolecules polysaccharides, polymers composed of many sugar building blocks
monosaccharides single sugars
Lactose milk sugar
glucose storage polysaccharide in plants consists entirely of glucose monomers
Where is glucose mainly stored in Human and other vertebrates? liver and muscle cells
helix spiral shaped
hydrolyze to break down
What are examples of alpha glucose? starch and glycogen
What is an examples of beta glucose? cellulose
microfibrils the strong building materials of the plant cell wall formed by parallel cellulose molecules
insoluble fiber cellulose in human food that passes through the digestive tract
what is the most common monosaccharide? glucose
antropod any invertebrate with joint legs
why are lipids hydrophobic? because they consist mostly of hydrocarbons which from non-polar covalent bonds
what are the most biologically important lipids? fats, phospholipids, and steriods
what are some storage polysaccharides? starch, glycogen, glucose and cellulose
glucose + galactose = ? lactose
sucrose common table suger
How man lbs of glycogen can the liver hold? 2 to 3 lbs
glucose + glucose = ? maltose
glucose + fructose= ? sucrose
glycogen vs. starch glycogen differs from strach because it has more branches
glycerol a 3 carbon alcohol with a hydroxyl group attached to each carbon
ester linkage Linkage between fatty acid and a glycerol.
when are saturated fats are solid ? at room temperature
when are unsaturated fats are liquid? at room temperature
give an example of a saturated fat? animal fats
give an example of a saturated fat? plant and fish fats
What does hydrogenating vegetable oils create? unsaturated fats with trans double bonds
Which fats contribute to cardiovascascular disease? saturated and trans fats
Which fats contribute to cardiovascascular disease more ? trans fats
What is the major function of fats? to store energy
Where do humans and other mamals store their fat? adipose cells
adipose tissue cushions vital organs and insulates the body
Are phospholipids hydrophobic? The two fatty acid tails are hydrophobic, but the phosphate group and its attachments form a hydrophilic head
What happens when phospholipids are added to water? they self assemble into a bilayer with the hydrophobic tails pointing toward the interior
What is the major component of all cell membranes? phospholipids
high levels of ______ the blood may contribute to cardiovascular disease ? cholesterol
catalyst a substance that causes or accelerates a chemical reaction without itself being affected
A proteins consists of how many polypeptides? one or more
peptide bonds links amino acids together
Each polypeptide has a unique linear sequence of ______________. amino acids
Interactions between R groups include __________ bonds. hydrogen and ionic bonds
Interactions between R groups include __________interactions. hydrophobic and van der Waals interactions
Collagen a fibrous protein consisting of three polypeptides coiled like a rope
Hemoglobin a globular protein consisting of four polypeptides: two alpha and two beta chains
Sickle Cell diesease an inherited blood disorder, results from a single amino acid substitution in the protein hemoglobin
Ribosomes where Protein synthesis occurs
Two types of Nucliec Acids: DNA and RNA
Each nucleotide consists of a __________base, a ________ sugar and ___________ group nitrogenous,pentose, and phosphate
nucleoside The portion of a nucleotide without the phosphate group
nitrogenous base + sugar = Nucleoside
The two families of nitrogenous bases: Pyrimidines and Purines
An examples of Pyrimidines cytosine, thymine, and uracil
An examples of Purines adenine and guanine
nucleoside + phosphate group Nucleotide
plamsa membranes cell membrane
Protein Enzymes act as a catalyst to speed up chemical reactions

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