1.
.3mg: How much epinepherine does an adult Epipen contain?
2.
.15mg: How much epinepherine does a child Epipen contain?
3.
1/2: about how many of the undifferentiated lymphocytes travel by blood vesselsto lymph tissue?
4.
2,000 antibodies each second: How many antibodies can plasma cells produce?
5.
10 sec.: How long must the epipen stay in the muscle?
6.
30 min: how long will it take for type 1 allergic reactions to usually occur?
7.
90%: What % of antibodies are IgG?
8.
a protein substance which is produced by plasma cells and is programmed to destroy a specific antigen: What is an antibody?
9.
Acantholysis: is the disruption of the intercellular bridges of the stratum spinsoum layer of the epithelium?
10.
acantholysis: when desmosomes are destroyed the cells are no longer held together...this is called?
11.
allergy: An exagerated immune response to an antigen is?
12.
Antigen: Any substance that the body recognizes as foreign
13.
Autoimmune disease: a disease in which the body recognizes its own cells as antigens and tries to destroy them
14.
B cells and antibodies: What does type 1 allergies involve?
15.
B lymphocytes: once the undifferentiated lymphocytes travel to the lymph tissue what do they mature into?
16.
B lymphocytes, plasma cells and antibodies: What is responsible for Humoral Immunity?
17.
bone marrow: where do most immature lymphocytes begin life?
18.
Cell-Mediated Immunity: The T lymphocyte are responsible for what kind of immunity?
19.
cytokines (IL-1, TNF) Interleukin 1 and tumor necrosis factor: What do the T cells start secreting when they recognize the anigen that they have been programmed to destroy?
20.
desmosomes: what are the intercellular structures that hold the epithelial cells together?
21.
hemidesmosomes: what glues epithelium to the connective tissue and junctional epithelium to the tooth?
22.
IgE (Type 1 only!): Which antibody does type 1 allergic reactions involve?
23.
immediate vasodialation and bronchoconstriction: What is the 4th step in a type one allergic reaction?
24.
Immune complex: an antibody plus and antigen
25.
Immunodeficiency: a deficiency of the immune response wither from decrease numbers of lymphocytes (T or B cells) or malfunctiong T and B cells
26.
immunoglobulin: What is an antibody also called?
27.
in blood of patients with Rheumatoid Arthritis and other autoimmune diseases such as Systemic Lupus and Sjorgren's Syndrome: Where is Rheumatoid Factor commonly found?
28.
in the bone marrow from stem cells: Where are undifferentiated lymphocytes produced?
29.
its own cells: In an autoimmune disease the body produces antibodies against what?
30.
leukoedema, pemphigus vulgaris: What causes Acantholysis?
31.
lymph nodes: where do the undifferentiated lymphocytes primarily travel to?
32.
lymph nodes, spleen,and other tissues of the body: Where do the Mature Tcellsthen travel to?
33.
plasma cells: What do B lymphocytes further mature into?
34.
Rheumatoid factor: an autoantibody that will actually bind to other antibodies (IgG) preventing that antibody (IgG) from being effective
35.
several hrs. to days: How long will it take for a type 4 allergic reaction to occur?
36.
specific antibodies: What do the plasma cells produce?
37.
stratum basale: what is the deepest layer of the keratinized epithelium?
38.
T Cells: What happens to these cells once they are in the Thymus Gland?
39.
T cells: What are T lymphocyes also called?
40.
Tcells (T helper cells)and the substances they produce: What does type 4 allergic reactions involve?
41.
These IgE antibodies bind to mast cells: What is the 2nd step in a type one allergic reaction?
42.
Thymus: a lymphiod organ located between the sternum and the heart
43.
Thymus Gland: Where does the blood stream carry the other half of the undifferentiated lymphocytes that are produced in the bone marrow to?
44.
Type 1 and Type 4: What are the two types of allergic reactions?
45.
vasodilation adn chemotaxis of WBC's: What do the cytokines cause?
46.
We are exposed to an antigen and our body reacts by producing IgE antibodies: What is the 1st step in a type one allergic reaction?
47.
We are exposed to this antigen again, the antibody recognizes the antigen and stimulates the mast cell to release its histamine: What is the 3rd step in a type one allergic reaction?
48.
when it is exposed to an antigen that fits into its receptor site: when can b lymphocytes mature into a plasma cell?
49.
Xeropthalmia: dry eyes
50.
Xerostomia: Dry mouth
