6 parts of non-specific immunity
external barriers, phagocytosis, inflammation, natural killer cells, fever, interferon & complement
Non-specific level of defense
level of defense that attacks or forms a barrier to all antigens.
non-specific immunity is also known as________
3 external barriers
epithelial linings - acidity, dead surface cells, flakes off.
hair follicles, sweat glands
mucosa and cilia
5 internal barriers
phagocytosis & chemical release, inflammation, killer cells, fever, interferon & complement.
when a leukocyte, a.k.a. white blood cell (neutrophil, monocyte, eosinophil) encapsulates and consumes and antigen.
first responders, they release bleach.
later responders. produce toxic chemicals. elevated levels in chronic infection.
consume antigens after they have been identified and coated with anti-bodies.
The 3 phagocytic cells are_____ ______ ______
neutrophils, monocytes, eosinophils
antigen presenting (def.)
the 3 phagocytic cells consume the antigens and then regurgitate/display the antigen markers, so that the T- and B-cells can recognize - thus triggering adaptive immunity, or specific defense.
Inflammation response (3 parts)
release of chemicals (histamine for vasodilation)
isolation of damaged areas (fibrinogen)
lymph drainage (takes antigen into lymph nodes)
Natural killer cells
lymphocytes that detect abnormal cells in our body and attack them.
macrophages release chemicals targeting the hypothalamus to raise body temperature to help fend off bacteria and virus.
a protein chemical that 'interferes' with virus development.
What 3 things release interferon?
lymphocytes, macrophages, tissue cells surrounding infected cell.
Action of interferon (4 things)
'warns' other cells, inhibits virus from multiplying, contains virus until specific immunity can take action, stimulates lymphocytes to attack and kill infected cells.
a surface-bound enzyme in our cells. can cause invading cell to rupture. Causes vessel dilation, and enhances inflammation.
The cells that attack cancer cells are________
natural killer cells.