5 Written Questions

1. intracellular []-5-15 mM
   extracellular []-145 mM
2. (1) coupled transporter
   (2) atp-driven pumps
   (3)light driven pumps
3. causes alot of diversity because it forms OH branch on glucose
4. couple uphill transport to they input of energy from the light
5. -maintain low level of Calcium in the cytosol
   - four different subunits
   -allosteric protein
   -pumps Ca back into SR after contraction in skletal muscle
   -10 alpha helices
   -conformational change by phosphorylation

5 Matching Questions

1. Ch.12: Ion channels and the membrane potential
2. Ch. 12: Membrane transport protein fall into two classes: (1)channels
3. ch.12: active transport
4. ch.12: potassium electrochemical tradient
5. ch.12: electrochemical gradients:

1. a few channels form large pores
   proteus form gap junction between adjacent cells
   porins form channels in outer membrane
   aquaporin facilitates flow of H20 across the pm
   prohibits ions
2. b K+ low outside, high inside
3. c moving molecules against the electrochemical gradient (takes energy)
4. d net charge and solute concentration determine gradient size and direction
5. e disciminate mainly molecules that are small enough and carries the appropriate charge and can slip through a narrow trapdoor

5 Multiple Choice Questions

1. probability of being open is controlled by membrane potential
   1. Ch. 12: Membrane transport protein fall into two classes: (1)channels
   2. ch.12: membrane potential is created by
   3. Ch. 12: Solutes cross membranes either passive or active: active
   4. Ch.12:Voltage gated Ion channels respons to membrane potential; voltage gated channel
2. (1) voltage gated channels
   (2) ligand gated channels
   (3) stress-gated channels
   1. Ch.12: lon channels are ion-selective and gates; are not continuously open; 3 ways opened
   2. Ch.12: Concentration and electrical forces drive passive transport
   3. Ch.12: lon channels are ion-selective and gates
   4. Ch.12: Ion channels and the membrane potential
3. net driving force ([] gradient and voltage)
   determines directino of passive transport across membrane
   1. Ch. 12: Transporters and functions:
   2. Ch. 12: Transporters and functions: plasma membrane
   3. Ch. 12: Transporters and functions: lysosome
   4. Ch. 12: Transporters and functions: electrochemical gradinet
4. 1) coupled transporter
   2)ATP-driven pump
   3) light-driven pump
   1. ch.12: passive transport
   2. ch.12: active transport: 3 ways to make it go
   3. ch.12: Each transporter in the cell membrane
   4. ch.12: coupled active transport: symport
5. difference in charges extracellular (+) and intracellular (-), on each side of the membrane
   1. ch.12: acetylcholine
   2. ch.12: channel proteins
   3. ch.12: carrier protein
   4. ch.12: membrane potential

5 True/False Questions

1. ch.12: lysosomes- why do we need a low pH? → -are the home of acid hydrolases
   -enzymes that work at low pH

   True        False

2. ch.12: Na/ K pump → -maintain low level of Calcium in the cytosol
   - four different subunits
   -allosteric protein
   -pumps Ca back into SR after contraction in skletal muscle
   -10 alpha helices
   -conformational change by phosphorylation

   True        False

3. Ch.12: Intracellular Ca2+ [] are kept low by Ca2+ → can bind to protein, alters activit
   occurs in SR
   Ca+ contains 4 domains
   muscle stimulated, Ca+ floods from SR to cytosol
   Ca+ returned to SR by Ca+ pump
   cross membrane as 10 alpha helices
   ATP binding and phosphorylation trigger conformational change
   rearranges transmembrane helices
   eliminates Ca_ binding sites and release Ca+ ions into lumen of SR

   True        False

4. Ch.12:Voltage gated Ion channels respons to membrane potential; Ion channels → controlled by the ligand of some molecule to the channel

   True        False

5. Ch.12:Voltage gated Ion channels respons to membrane potential;ligand- gated channels → controlled by the ligand of some molecule to the channel

   True        False