| Term | Definition |
| obdurate | Stubbornly persistent or determined; resistant to persuasion |
| obfuscate | To confuse; to make obscure |
| obstinate | Unreasonably persistent or stubborn |
| olfactory | Relating to the sense of smell |
| oligarchy | A government in which a small group holds all of the control |
| onus | A burden or obligation |
| opine | To express an opinion or feeling |
| opportunist | One who takes advantage of any chance to achieve an end, with little regard for morals or principles |
| opprobrious | Disgraceful; shameful |
| ornery | Having an irritable disposition or mood; cantankerous |
| oscillate | To swing back and forth like a pendulum; to vary between opposing beliefs or feelings |
| ossify | To change into bone; to become hardened or set |
| ostracize | To exclude or reject from a group by common consent |
| oust | To remove a title or position by force; eject |