Vessels, arteries, veins, pumping organ
What the blood vascular system is comprised of
Move blood away from the heart (Efferent)
move blood toward the hear (afferent)
Pulmonary circulation, portal circulation, systematic circulation
the three types of circulation
Lymph and Blood Vascular system
What the Circulatory system is comprised of
where does the lumph system begin?
Anterior Vena Cava
where does the lymph system end?
lacks proteins, contains lymphocytes
How is lymph different than blood plasma?
help Fight foreign invaders
The purpose of lymphocytes
Transport gasses, nutrients, waste, regulatory substances
ct as clotting mechanism
Functions of the circulatory system
vitamins, minerals, hormones, enzymes
types of regulatory substances
Main, body defense
2 clotting mechanisms
the pH of blood
oxygenated blood color
deoxygenated blood color
Cellular elements, plasma
Major components of blood
Another name for RBC's
types of WBC's
Neutrophylls, esinophylls, basophylls
Funciton of plasma
does serum have a clotting factor?
Myeloid tissue, lymphoid tissue
2 basic areas of blood production
where is myeloid tissue found
RBC, granular WBC's Platelets
What is produced in the myeloid tissue
what is produced in the lymphoid tissue
Red, Yellow, White, gelatenous
4 types of myeloid tissue
red myeloid forms what?
decreaced RBM increased YBM
As an animal ages what happens to bone marrow amounts?
Ribs, sternum pelvis, sometimes vertebrae
where is RBM found in an adult?
Longbones, femur, ulna
where is RBM found in young animals?
when can YBM revert back to RBM?
transport O2 and CO2
function of erythrocytes
65% Water, 33% Hemoglobin, 2% mix protein, lipid, vitamin, mineral
Composition of RBC
shape of RBC
diameter of RBC
how many RBC's are in one cc of blood?
describe the nucleus of an RBC
A mature RBC is called
an immature RBC is called
weblike appearance (bluish threads) within the cell
What do reticulocytes appear like?
how many molecules of hemoglobin are in one RBC?
Principle transport medium of blood
function of Hb
increased production of Hb for more effecient gas exchange
Hb + O2
how many iron receptors are on one molecule of Hem?
How many molecules of hem are there per globin?
how many O2 can 1 Fe++ carry
how many possible molecules of O2 can be carried by one Hb?
where are RBC's formed?
Precursor cell to RBC's found in the RBM (nucleated cell)
hemohistoblast --> arithroblast --> Reticuloblast --> reticulocyte --> Arithrocyte
outline the formation of RBC's
hormone regulation and nervous system
what is RBC under the control of?
hypoxia -->hypothalamus signals kidneys to secrete erythropoitea --> targets RBM --> increased production of RBM
outline the stress-induced increased production of RBC's (reversion of RBM)
lifespan of a RBC
AVG life of an RBC
responsible for the removal of old RBC's
destruction of red blood cells with liberation of hemoglobin into the surrounding medium
Porphyrin ring and iron
structure of Hem
Amino Acid material
what is globin constructed of?
portion of Hem that is reused
portion of Hem that is not reused
How is the used porphyrin ring disposed?
Neutrophils, Eosinophils, Basophils
types of Granular WBC's
Contains a many lobed nucleus, acts as the first line of defense, is actively amoeboid and phagocytic, helps fight acute infections
what do neutrophils help fight?
Increase during chronic or parasitic infections, amoeboid in shape, increase during allergic Rxns and detoxify forein proteins
proportion of WBCs that are neutrophils
proportion of WBC's that are Eosinophils
Not present in any significant #,
will increase during leukemia, small pox, Hodgkins, disease, Chicken pox
2 types of Agranular WBC's
An agranular leukocyte that is able to migrate into tissues and transform into a macrophage.
amoeboid cells which form antibodies to increase immunity
large and small
the 2 types of lymphocytes
smalles blood element, which origniates in the megacarocyte. Produces thrombokinase
Another name for bone marrow
enzyme used in blood clotting process
90% H20 10% solids
amino acid material (peptide, polypeptide)
regulatory compounds (hormones and enzymes)
solids found in the blood conist of?
fibrinogen, globulins, albumin, albimunen
types of proteins foudn in plasma-fluid portion of the blood
form and impervious cover for damaged tissue to keep out foreign material
purpose of clotting
sequential series of enzymatic reactions upon various substrates
when plateletes rupture
when is thrombokinase released?
thrombokinase combines with ionized calcium and attacks prothrombin
what happens when ruptured platelets come in contact with damaged tissue
plasma protein; converted to thrombin in the clotting process
A blood protein essential to blood clotting. The conversion of fibrinogen to its active form (fibrin) is among the final steps in clot formation, and is triggered by thrombin.
decreased temperature, venoms, liver trauma
factors which slow down clotting time
increased temperature, adrenalines, contact with rough texture
factors which speed up clotting time
where does the anatomy of the blood circulatory system begin and end?
a double-layered serous membrane that surrounds the heart
outermost layer of the heart
inner lining of the heart
thick middle muscle layer of the heart; pumps blood through the circulatory system
upper chamber of the heart that receives and holds blood that is about to enter the ventricle
a chamber of the heart that receives blood from an atrium and pumps it to the arteries
valve which separates the atrium and ventricle
tubular structures which carry blood away from the heart
large arteries are?
maintains blood pressure
a function of arteries
smaller, thinner branches of arteries, carry blood to capillaries
terminations of arterioles which supply cappilaries
position of smooth muscle sphinctors located in arterioles
prevent backflow into the capillaries
one purpose of arterioles
tiny, thin-walled blood vessels that allow the exchange of gases and nutrients between the blood and the cells of the body
smalles veins that carry blood toward the heart
blood vessels that carry waste containing blood from the tissues back to the heart
veins are usually _______ than the corresponding arteries