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5 Written questions

5 Matching questions

  1. to break down 1 glucose molecule you need ___ NAD+ from inside & ____ NAD+ from outside mitochondria, ___ oxaloacetate, _____ ADP, and ____ of each enzyme
  2. isocitrate
  3. step 7
  4. step 1
  5. what can Acetyl-CoA be turned into?
  1. a 8 (2 from pyruvate to acetyl coa, 6 from krebs), 2 (glycolysis), 1, 4, 1
  2. b fats, ketone bodies, cholesterol (NOT glucose!)
  3. c oxaloacetate (4c) is condensed with an acetyl group (2c) to form citrate (6c) with the help of citrate synthase
  4. d fumarate (4c) is transformed into malate (4c) with the help of fumarase, bringing in 1 molecule of H2O
  5. e a secondary alcohol that is oxidized to a ketone (alpha-kg)

5 Multiple choice questions

  1. ATP, NADH, succinyl CoA
  2. isocitrate (6c) is oxidized to form alpha-ketoglutarate (5c) with the help of isocitrate dehydrogenase, transforming NAD+ into NADH and releasing H+ and CO2
  3. its coenzymes include b-vitamins (water soluble) that act as recyclable prosthetic groups; it's the most irreversible reaction in our body/there's no getting around it, so once acetyl-CoA is made, you cannot go back
  4. pyruvate + NAD+ + CoA-SH (coenzyme A) ----pyruvate dehydrogenase complex---> CH3C(=O)SCoA (acetyl coa) + NADH + CO2
  5. alpha-ketoglutarate (5c) is oxidized to form succinyl coA (4c) with the help of alpha-ketoglurate dehydrogenase complex, transforming NAD+ into NADH, bringing in CoA, and releasing CO2 and H+

5 True/False questions

  1. where does it take place?inner mitochondrial matrix

          

  2. FADa 2-electron oxidizing agent that is reduced to NADH; comes from nicatinamide, or niacin

          

  3. how krebs differs from glycolysisinner mitochondrial matrix

          

  4. what is citrate?the conjugate base of citric acid; a tertiary ROH that is not easily oxidized (that's why it's isomerized in the cycle)

          

  5. step 2citrate (6c) is isomerized to isocitrate (6c) with the help of aconitase

          

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