5 Written Questions
5 Matching Questions
- which intermediates of the krebs cycle can be made into glucose?
- to break down 1 glucose molecule you need ___ NAD+ from inside & ____ NAD+ from outside mitochondria, ___ oxaloacetate, _____ ADP, and ____ of each enzyme
- where does it take place?
- step 8
- what kinds of things inhibit the enzymes at the control points?
- a inner mitochondrial matrix
- b all of them
- c ATP, NADH, succinyl CoA
- d 8 (2 from pyruvate to acetyl coa, 6 from krebs), 2 (glycolysis), 1, 4, 1
- e malate (4c) is oxidized into oxaloacetate with the help of malate dehydrogenase, transforming NAD+ into NADH and releasing H+
5 Multiple Choice Questions
- fats, ketone bodies, cholesterol (NOT glucose!)
- it's normous and requires pantothenic acid, a water soluble vitamin, to make it
- a 2-electron oxidizing agent that is reduced to NADH; comes from nicatinamide, or niacin
- a secondary alcohol that is oxidized to a ketone (alpha-kg)
- flavin adenine dinucleotide, a biological oxidizing agent that is reduced to FADH2; comes from riboflavin
5 True/False Questions
NAD+ vs. NAD: which is the better oxidizing agent? reducing agent? → pyruvate, fats, amino acids, ketone bodies
what is citrate? → a secondary alcohol that is oxidized to a ketone (alpha-kg)
step 2 → citrate (6c) is isomerized to isocitrate (6c) with the help of aconitase
step 3 → isocitrate (6c) is oxidized to form alpha-ketoglutarate (5c) with the help of isocitrate dehydrogenase, transforming NAD+ into NADH and releasing H+ and CO2
how krebs differs from glycolysis → no reversal needed, no quick mechanism for NAD+ regeneration (too oxidative), more acetyl-CoA available