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5 Written Questions

5 Matching Questions

  1. what can Acetyl-CoA be turned into?
  2. FAD
  3. there are ___ control points
  4. to break down 1 glucose molecule you need ___ NAD+ from inside & ____ NAD+ from outside mitochondria, ___ oxaloacetate, _____ ADP, and ____ of each enzyme
  5. step 3
  1. a flavin adenine dinucleotide, a biological oxidizing agent that is reduced to FADH2; comes from riboflavin
  2. b fats, ketone bodies, cholesterol (NOT glucose!)
  3. c 4 (3 within, 1 outside)
  4. d isocitrate (6c) is oxidized to form alpha-ketoglutarate (5c) with the help of isocitrate dehydrogenase, transforming NAD+ into NADH and releasing H+ and CO2
  5. e 8 (2 from pyruvate to acetyl coa, 6 from krebs), 2 (glycolysis), 1, 4, 1

5 Multiple Choice Questions

  1. a 2-electron oxidizing agent that is reduced to NADH; comes from nicatinamide, or niacin
  2. malate (4c) is oxidized into oxaloacetate with the help of malate dehydrogenase, transforming NAD+ into NADH and releasing H+
  3. succinate (4c) is oxidized into fumarate (4c) with the help of succinate dehydrogenase, transforming FAD into FADH2
  4. citrate (6c) is isomerized to isocitrate (6c) with the help of aconitase
  5. alpha-ketoglutarate (5c) is oxidized to form succinyl coA (4c) with the help of alpha-ketoglurate dehydrogenase complex, transforming NAD+ into NADH, bringing in CoA, and releasing CO2 and H+

5 True/False Questions

  1. what is citrate?a secondary alcohol that is oxidized to a ketone (alpha-kg)

          

  2. what can be turned into Acetyl-CoA?pyruvate + NAD+ + CoA-SH (coenzyme A) ----pyruvate dehydrogenase complex---> CH3C(=O)SCoA (acetyl coa) + NADH + CO2

          

  3. step 7fumarate (4c) is transformed into malate (4c) with the help of fumarase, bringing in 1 molecule of H2O

          

  4. what do you need to know about pyruvate dehydrogenase complex?its coenzymes include b-vitamins (water soluble) that act as recyclable prosthetic groups; it's the most irreversible reaction in our body/there's no getting around it, so once acetyl-CoA is made, you cannot go back

          

  5. pyruvate to acetyl-coathe conjugate base of citric acid; a tertiary ROH that is not easily oxidized (that's why it's isomerized in the cycle)

          

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