amyl nitrite
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11 terms
Terms | Definitions |
|---|---|
 What is the class of amyl nitrite? | coronary vasodilator |
| What is the description of aml nitrite? | - related chemically to nitroglycerine -effective in the emergency management of cyanide poisoning by causing oxidation of hemoglobin to the compound methemoglobin |
| What is the onset of amyl nitrite? | - 30 sec inhaled |
| What is the duration amyl nitrite? | 3 - 20 minutes |
| What is the indications for amyl nitrite? | - cyanide poisoning (only until sodium nitrite can be givne IV) |
| What is the contraindications of amyl nitrite? | - none when used for cyanide poisoning - severe anemia - hypersensitivity to nitrates |
| What are the side effects of amyl nitrite? | -hypotension - tachycardia - palpitations - syncope - headache - nausea |
| What are the drug interactions of amyl nitrite? | - none significant - alcohol can increase toxicity |
| How is amyl nitrite supplied? | - 0.3 mL/glass ampule - capsule covered with woven gauze |
| What is the dosage and administration of amyl nitrite? | - glass ampule should be broken - crush ampule and hold under patient's nostrils - inhale for 30-60 sec - may be repeated as necessary - one to six inhalations from one ampule usually is sufficient |
| What are the special considerations for amyl nitrite? | - pregnancy safety: category x - frequently abused (claimed to be an aphrodisiac) - also known as "amy" - cyanide poisoning often produces a bitter almond breath odor (not all persons can detect the odor) - patient should be supine during administration, and blood pressue should be monitored |
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