Ch 35 - Lymph System

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STABlake  on April 2, 2011

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Ch 35 - Lymph System

agglutination
a clumping of bacteria or red cells when held together by antibodies (agglutinins)
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Definitions

agglutination a clumping of bacteria or red cells when held together by antibodies (agglutinins)
allergen A substance that causes an allergic reaction
allergy reaction due to extreme sensitivity to certain foods, chemicals, or other normally harmless substances
anaphylactic shock a severe and rapid and sometimes fatal hypersensitivity reaction to a substance (especially a vaccine or penicillin or shellfish or insect venom) to which the organism has become sensitized by previous exposure
antibody-mediated immunity The production of antibodies by B cells in response to an antigen. Also called humoral immunity.
antigen substance that triggers an immune response
antigen-presenting cell (APC) macrophages and dendrite cells ingest a cell or particle, remove its antigens and display some of them on their cell surfaces
antigen receptor the general term for a surface protein, located on B cells and T cells, that bind to antigens, initiating aquired immune responses
apoptosis a type of cell death in which the cell uses specialized cellular machinery to kill itself
asthma chronic inflammatory disorder with airway obstruction caused by bronchial edema, bronchoconstriction, and increased mucus production
autoimmune disease any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
B lymphocyte (B cell) antigen produced by killer t cell after virus is destroyed
cell-mediated immunity an immune response in which killer T cells attack antigen-bearing cells directly
chronic inflammation inflammation of prolonged duration or slow progress marked histologically by an infiltration of mononuclear cells (lymphocytes, macrophages, plasma cells) often with proliferation of fibroblasts and fibrosis
clonal selection model states that the antigen selects which lymphocyte will undergo expansion and produce more lymphocytes bearing the same type of receptor
complement one of a series of enzymes in the blood serum that are part of the immune response
cytokine Protein (made by T lymphocytes) that aids antigen destruction
cytotoxic T cell T lymphocyte that directly kills foreign cells.
delayed allergic response repeated exposure to an antigen causes the body to mount an inflammatory response ( contact dermatitis)
dendritic cell specialized macrophage that digests foreign cells and helps B and T cells to mark antigens for destruction
edema swelling from excessive accumulation of serous fluid in tissue
foreign antigen stimulate antibody production or other immune responses - include bacteria, viruses, fungi, protozoa, and malignant cells
hay fever a seasonal rhinitis resulting from an allergic reaction to pollen
helper T cell lymphocyte that activates cytotoxic T cells and stimulates B cells to produce antibodies
histamine a regulating body substance released in excess during allergic reactions causing swelling and inflammation of tissues
immediate allergic response Body reacts immediately to an antigen causing body to have an acute reaction. The reaction will intensify after each exposure to the same antigen., due to the activity of antibodies; anaphylactic shock; bee sting
immunity Resistance to disease
immunization process by which resistance to an infectious disease is induced
immunoglobulin a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response, Ig
inflammatory response nonspecific defense against infection, characterized by redness, heat, swelling, and pain
interferon protein produced by cells in response to being infected by a virus; helps other cells resist the virus
interleukin a protein produced by certain white blood cells that regulates immune responses by activating lymphocytes and initiating fever
lymph the clear fluid that bathes each cell and transfers needed substances and wastes back and forth between the blood and the cells
lymphatic (lymphoid) organ organ other than a lymphatic vessel that is part of the lymphatic system; lymph nodes, tonsils, spleen, thymus gland and bone marrow
lymphatic system the interconnected system of spaces and vessels between body tissues and organs by which lymph circulates throughout the body
lymphatic vessel a vascular duct that carries lymph which is eventually added to the venous blood circulation
lymph node Organ located along a lymph vessel. Lymph nodes filter lymph and help attack viruses and bacteria.
macrophage Large white blood cell that removes bacteria, foreign particles, and dead cells
mast cell a large connective tissue cell that contains histamine and heparin and serotonin which are released in allergic reactions or in response to injury or inflammation
membrane attack complex the complex of terminal complement components that forms a pore in the membrane of the target cell, damaging the membrane and leading to cell lysis.
memory B cell do not secrete antibodies. Instead, they can quickly proliferate and differentiate into more plasma cells and more cells should the same antigen reappear at a future time.
memory T cell long-lived antigen-specific T cells that are activated in secondary and subsequent immune responses to an antigen., provide quick response on re-exposure
monoclonal antibody Antibody produced in a laboratory to attack specific antigens.
natural killer (NK) cell lymphocyte which recognizes and destroys foreign cells or infected host cells in a nonspecific manner
pathogen a virus or organism that can cause disease
Peyer's patches collections of lymphatic tissue found in the submucosa of the small intestine
plasma cell Lymphoid cell that secretes an antibody and originates from B lymphocytes
red bone marrow functions to form red blood cells, some white blood cells, and platelets; found in cavities of most bones in infants and in the flat bones in adults
self-antigen The body's own antigen
spleen a large dark-red oval organ on the left side of the body between the stomach and the diaphragm, Produces blood cells, destroys damaged blood cells, stores blood cells
T lymphocyte A type of lymphocyte responsible for cell-mediated immunity that differentiates under the influence of the thymus.
thymus gland gland that produces T lymphocytes and aids in the immune response
tonsils oval lymphatic tissues on each side of the pharynx that filter air to protect the body from bacterial invasion; also called palatine
vaccine immunogen consisting of a suspension of weakened or dead pathogenic cells injected in order to stimulate the production of antibodies
vermiform appendix wormlike projection of lymphatic tissue hanging off the cecum with no digestive function (may help fight infection)

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