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5 Written Questions

5 Matching Questions

  1. cirrhosis: fibrosis
  2. portal HTN complications
  3. choledocholithiasis
  4. insoluble bilirubin
  5. cirrhosis: dec bilirubin metabolism
  1. a => jaundice, clay stools/dk UA bleeding
  2. b indirect or unconjugated bilirubin
  3. c => portal HTN => ascites, edema, splenomegaly, varices

    => liver failure, hepatorenal failure => encaphalopathy => coma => death
  4. d stones in common bile duct
  5. e bleeding: varices => mild (melena) or severe (rupture red/coffe-ground = life threatening)
    bleeding: dec Vit K => dec clotting
    anemia: bleeding, dec storage B vit, dec Fe storage

5 Multiple Choice Questions

  1. viral, bacterial, parasitic, EtOH, drugs, toxins, transfusion reaction, autoimmune
  2. splenomegaly from inc splenic vein pressure
    ascites: from inc pressure mesenteric vessles => inc capillary permeability and dec COP => fluid shifting
    hepatic encaphalopathy
    hepatorenal syndrome
  3. inflammation of gallbladder
    dec blood flow => ischemia => necrosis and perforation
    stones often present in cystic duct
  4. obesity, middle age, female, familial
  5. rapid breakdown of RBCs => exceeds ability of liver to conjugate
    *inc unconjugated (indirect) bilirubin)
    *jaundice skin and sclera, pruritus

5 True/False Questions

  1. serology of hepatitis Binc fecal HA antigen (only serologic marker in incubation before jaundice (infectious)
    HAV rapidly clears with s/s (<infxn); inc liver enz and anti-HAV
    acute stage = inc anti-HAVE IgM


  2. hepatitis pathologyinflam of liver => varying severity of hepatic cell damage => kupffer cell hyperplasia => infiltration of phagocytes to necrosis and scarring => alters microvasculature => portal HTN => liver failure and death


  3. phases of hepatitis: prodromalhighly infectious 2 wks after exposure to onset of jaundice
    s/s is vague: malaise, fatigue, nausea, low-grade fever, sudden distaste for smoking/foods, joint pain


  4. toxic hepatitispoisonous mushrooms
    analgesics (tylenol, NSAIDs), anesthetics, statins, some anticonvulsants, anti-fungal, antibiotics
    anabolic steroids, anti-HTN, some herbs, industrial/chemicals/pesticides/herbicides


  5. hepatitis Atransmission: FECAL-ORAL
    hep A antigen
    anti-HAV antibody
    NO chronicity
    30 days incubation


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