macrocytic/normo
About this set
Created by:
elkompachuy on April 9, 2011
Subjects:
Log in to favorite or report as inappropriate.
Order by
14 terms
Terms | Definitions |
|---|---|
 macrocytic anemias | FAB, folate deficeincy, alcoholism, b12-deficeincy |
| folate deficiency cause | inadequate intake, alcoholics, elderly, intestine ds, meds like methroxate |
| The patient is an old alcoholic male, with low serum folic acid, high LDH, Smear show macroovalocytes what the TX | Give folic acid , for folic deficiency |
| *For folic deficiency TX, large doses of pheytoin may cause | increase frequency of seizures |
| A chronic alcoholic patient, AST>ALT, smear shows: Stomatocytes and Target cells, tx | Abstinence from alcohol and nutritional counseling. B12 or folic acid given if needed |
| Most B12 is stored in the liver, 1-10 mg, | which is a sufficient amount to support erythropoiesis for 2-5 years.* |
| B12 Deficiency: also known as | megaloblastic anemia. |
| patient has bilateral paresthesia of hands and feet. slowed reflexes.loss of memory/confusion.*Glossitis: beefy red tongue * | B-12 Deficiency |
| Pernicious Anemia | the most common cause of adult B12 deficiency. autoimmune where an anti-intrinsic factor antibody attacks the parietal cell which decreases transport of B12. |
| Pancreatitis: (B12 deficiency) | inflammation of the pancreas decreases release of intrinsic factor.* |
| Schilling test < 7% excretion:, Hypersegmented neutrophils , MCV > 100, macroovalocytes what tx | megaloblastic anemia, depends on Shilling test but other causes respond to Intramuscular injection of 1000 micrograms of Cyanocobolamin weekly for 4-6 weeks, then monthly for life. |
| Schilling Test, STAGE B12 ↓ excretion STAGE 2 B12/IF ↑ excretion STAGE 3 AFTER ABX N/A | Pernicious Anemia , Gastric Atrophy |
| Schilling Test,STAGE 1 B12↓ excretion, STAGE 2 B12/IF, STAGE 3 ABX ↓ excretion ↑ | Bacterial Overgrowth excretion Diphyllobothriasis |
| Schilling Test, ALL 3 STAGES DECREASE EXCRETION | Terminal Ileum , Disease (Crohn's) |
First Time Here?
Welcome to Quizlet, a fun, free place to study. Try these flashcards, find others to study, or make your own.