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neural integration

neural integration

the ability of your neurons to process information, store and recall it and make decisions

excitatory postsynaptic potential (EPSP)

usually results from Na+ flowing into the cell and cancelling some of the negative charge on the inside of the membrane

inhibitory postsynaptic potential (IPSP)

some are produced by a neurotransmitter opening ligand-regulated chloride gates causing Cl- to flow into the cell and make the cytosol more negative

EPSP

any voltage change in that direction makes a neuron more likely to fire and is therefore called

IPSP

a neurotransmitter hyperpolarizes the postsynaptic cell and makes it more negative than the RMP - this makes the postsynaptic cell less likely to fire

chemical synapses

are the decision making devices of the system.

glutamate and aspartate

are excitatory brain neurotransmitters that produce EPSPs.

glycine and GABA

produce IPSPs and are therefore inhibitory

ACh and norepinephrine

are excitatory to some and inhibitory to others, depending on the type of receptors present on the target cell

EPSP, IPSP

Some incoming nerve fibers produce __________, while others produce _____________.

net

The neuron's response depends on whether the ________ input is excitatory or inhibitory.

Summation

is the process of adding up post synaptic potentials and responding to their net effect

trigger zone

Summation occurs in the ______________

decisions

It is fundamentally a balance between EPSPs and IPSPs that enable the nervous system to make ________.

single action potential

A __________ in a synaptic knob does not produce enough activity to make a postsynaptic cell fire.

temporal summation and spatial summation

There are two ways to reach threshold and cause a postsynaptic neuron to fire

temporal summation

occurs when a single synapse generates EPSPs so quickly that each is generated before the previous one fades

spatial summation

occurs when EPSPs from several different synapses add up to threshold at the axon hillock.

groups

Neurons routinely work in ___________ to modify each other's actions.

facilitation

is a process in which one neuron enhances the effect of another.

presynaptic inhibition

is the opposite of facilitation, it is the mechanism in which one presynaptic neuron supresses another one.

qualitative, quantitative

The nervous system myst interpret and pass along both ______________ and ____________ information about its environment.

neural coding

the way in which the nervous system converts information to a meaningful pattern of action potentials is called _______________.

sensory coding

another name for neural coding

labeled line code

the most important mechanism for transmitting qualitative information is the ______________.

labeled line code

is based on the fact that each nerve fiber to the brain leads from a receptor that specifically recognizes a particular stimulus type

communication

Each nerve fiber to the brain is a line of __________ recognized by the brain, as representing a particulr stimulus quality - the color of light, pitch of sound, salty or sour taste.

Quantitative information

information about the intensity of the stimulus

recruitment

bringing additional neurons into play as the stimulus becomes stronger is called...

absolute refractory period

there is a limit to how often a neuron can fire, set by its __________________.

lowest, high threshold

A weak stimulus excites neurons with the __________ thresholds, while a strong stimulus excitesless sensitive _____________ neurons.

CNS

The __________ can judge stimulus strength from the firing frequency of afferent neurons.

mild stimulus

A _______________ excites sensitive low-threshold nerve fibers.

neural pools

neurons function in larger ensembles called __________ each of which consists of thousands to millions of interneurons concerned with a particular body function.

discharge zone

part of input neuron when acting alone can make the post synaptic cells fire

facilitated zone

broader zone where the neurons synapses with still other neurons in the pool with fewer synapses on each of them. it can stimulate those neurons to fire only with the assistance of other input neurons

facilitated zone

In _______________ the presynaptic neuron lacks enough synaptic contacts with a postsynaptic neuron to induce firing by itself -- but it can collaborate with other presynaptic neurons, facilitating each other in making the postsynaptic cell fire

discharge zone, spatial summation

In the _____________ the presynaptic input neuron has so many synaptic contacts with each postsynaptic neuron that it alone can induce the postsynaptic cell to fire, employing ____________.

neural circuit

The functions of a neural pool are partly determined by its ______________ the pathways among its neurons.

diverging circuit, converging circuit, reverberating circuit, parallel after-discharge circuit

Name the four principal kinds of neural circuits.

diverging circuit

one nerve fiber branches and synapses with several poststynaptic cells

diverging circuit

this type of neural circuit makes it possible for one motor neuron of the brain to ultimately stimulate thousands of muscle fibers.

converging circuit

is the opposite of a diverging circuit - input from many different nerve fibers is funneled to one neuron or neuron pool

converging circuit

this type of neural circuit allows input from our eyes, inner ears and stretch receptors in the neck to be channed to an area of teh brain concerned with the sense of balance.

reverberating circuit

neurons stimulate each other in a linear sequence A-->B-->C-->D, but neuron C sends an axon collateral back to A and restimulates

parallel after-discharge circuit

an input neuron diverges to stimulate several chains of neurons

reverberating circuit

this type of neural circuit sends repetitious signnals to your diaphragm and intercostal muscles to make you inhale

parallel after-discharge circuit

this type of neural circuit explains why you can stare at a lamp, then close your eyes and continue to see an image for a while

feedback loop

Unlike a reverberating circulit, parallel after-discharge circuit has no _______________.

after-discharge

Continued firing after the stimulus stops is called _____________.

memory trace (engram)

The physical basis of memory is a pathway through the brain called a _________________ in which new synapses have formed or existing synapses have been modified to make transmission easier.

synaptic plasticity

synapses can be formed or deleted in as little as 1 to 2 hours, this ability of synapses to change is called ___________.

synaptic potentiation

a form of synaptic plasticity - the process of making transmission easier.

immediate, short term, long term

Name 3 most recognizeable forms of memory

immediate memory

is the ability to hold something in mind for just a few seconds

immediate memory

this form of memory might be based on reverberating circuits

short-term memory

lasts from a few seconds to a few hours

working memory

is a form of STM that allows us to hold an idea in mind long enough to carry out an action such as calling a telephone # we just looked up or working out the steps of a math problem.

synaptic facilitation

somewhat longer lasting memories probably involve an effect called _________________-induced by tetanic stimulation, the rapid arrival of repetitive signals at a synapse.

posttetanic potentiation

The increased size of postsynaptic membrane potentials after tetanic stimulation.

long term memory

lasts up to a lifetime and is less limited than STM in the amount of information it can store.

declarative and procedural

List the 2 forms of long-term memory

declarative memory

the retention of events and facts that you can put into words - numbers, dates, and so forth

procedural memory

the retention of motor skills - how to tie your shoes, play a musical instrument,

LTM

Some ___________ involves the physical remodeling of synapses or the formation of new ones through the growth and branching of axon terminals and dendrites.

dendritic spines

In the pyramidal cells of the brain, the dendrites are studded with knob-like ____________ that increase the area of synaptic contact.

long-term potentiation

LTM can also be grounded in molecular changes called ____________________.

long-term potentiation

An increase in a synapse's firing potential after brief, rapid stimulation. Believed to be a neural basis for learning and memory.

Alzheimer and Parkinson diseases

are the two most common degenerative disorders of the brain. Both are associated with neurotransmitter deficiencies.

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