Hershey and Chase Study
determined that DNA is the genetic material of inheritance; bacteriophage study
the idea that bacteria take up DNA from their environment;
a change in genotype and phenotype due to the assimilation of external DNA by a cell
Semiconservative Model of DNA Replication
when a double helix replicates, each of the two daughter molecules will have one old strand, derived from the parent molecule and one newly made strand.
Single-Strand binding proteins
keeps strands of DNA from recombining, binds to and stabilizes single-stranded DNA until it can be used as a template
adds the RNA Primer; Synthesizes an RNA primer at 5 prime end of leading strand and of each Okazaki fragment of lagging strand
installs new nucleotids; catalyzes the snythesis of new DNA by adding nucleotides to a pre-existing chain.
Joins partial strands together; joins 3' end of DNA that replaces primer to rest of leading strand and joins Okazaki fragments of lagging strand
Wrote "Inborn errors of metabolism: was based on his research on a disease called "alkaptonuria or when urine turns black"
Avery, Macleod and McCarthy Study
Treated the DNA with two enzymes, a protease degrades proteins; DNAse degrades DNA.
The strand of the DNA double helix that is copied by a base pair complementary to make an RNA.
The original molecule; the parental double helix remains intact and an all-new copy is made.
Each strand of both daughter molecules contains a mixture of old and newly synthesized parts.
Top end and bottom end are not parallel, 5 prime has phosphate end and 3 prime has an OH- end.
and enzyme that adds segments to ends of molecules of DNA/seals the ends acts like bumpers.
highly alkaline proteins found in eukaryotic cells nuclei that package and order the DNA into structural units called nucleosomes
a region of DNA typically found near the middle of a chromosome where two identical sister chromatids come closest in contact.
In Eukaryotic chromosomal DNA molecules that have a special nucleotide sequence such as TTAGGG
a structure has two branching "prongs", each one made up of a single strand of DNA. These two strands serve as the template for the leading and lagging strands which will be created as DNA polymerase matches complementary nucleotides to the templates.
bead-like structures with 140 base pairs of DNA wrapped around a disc of eight histone proteins.
special proteins that help link mucleosomes together for communication and support
is acidic, negatively charged and associated with postiviely charged histone proteins.