Clinical Case 558 (71)

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Created by:

stevenypark Plus on April 27, 2011

Subjects:

neuroscience

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Clinical Case 558 (71)

What is the formula for pack-years?
number of packs smoked per day x years as a smoker
1/11

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What is the formula for pack-years? number of packs smoked per day x years as a smoker
Review 6 possible locations of lesions that could cause decreased pain and temperature sensation on the right side of the face. left S1 (hemisphere, lateral aspect - homonculus)

right CN 5 (pons)

left ventral trigeminal tract

thalamus

posterior limb internal capsule

right spinal trigeminal tract and nucleus (medulla)
Dysarthria and dysphagia suggest damage to which 3 structures? CN 9, CN 10 and/or nucleus ambiguus
Damage to which 2 structure causes singultus? reticular formation

CN 10

*medulla
Lack of elevation of the palate suggests damage to which neural structures (4)? corticobulbar fibers

CN 9, CN 10, nucleus ambiguus
Describe the ALS pathway.
primary sensory neuron synapse at substantia gelatinosa

secondary sensory neurons cross to contralateral side

ascension in ALS fiber tract

synapse at VPL nucleus of thalamus

posterior limb and corona radiata

primary somatosensory cortex S1
Name 3 structures that, if lesioned, could cause Horner syndrome. descending hypothalamospinal fibers

sympathetic preganglionic neuron

sympathetic postganglionic neuron
Lesion to which cerebellar peduncle can cause gait ataxia? inferior cerebellar peduncle (vestibulocerebellar, olivocerebellar and posterior spinocerebellar afferents)
Damage to which structure in the medulla causes tendency to veer to the right side? right vestibular nuclei
Name 6 structures damaged in wallenberg syndrome. ALS

central sympathetic pathway

spinal trigeminal tract and nucleus

inferior vestibular nucleus

nucleus ambiguus

reticular formation
Describe the spinal trigeminal pain pathway.
primary sensory neuron in trigeminal ganglion

enter through substance of the pons but descends in spinal trigeminal tract

synapse with secondary sensory neurons at spinal trigeminal nucleus

secondary sensory neuron cross at lower medulla

neuron travels through the ventral trigeminal thalamic tract to the thalamus (VPM nucleus)

tertiary go to axon of posterior limb of internal capsule to primary somatosensory cortex

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