The removal of abnormal RBC's from the blood by the spleen.
Formation produces erythrocytes, as well as WBC's in the developing.
RBC's production is preformed only in cases of severe hemolytic anemia.
Removal of worm out and abnormal RBC's and platelets from the bloodstream by phagocyte cells in the spleen
Removal of nuclei from old RBC's by the spleen w/o destroying the cell
85% composed of a framework of splenic sinuses altering with splenic cords (cords of Billroth responsible for blood storage and phagocytosis. spleen parenchyma. Splenic sinuses and splenic)
Responsibility of phagocytosis of damaged or old cells and their debris, foreign materials and pathogens taking them out of circulation in blood. In spleen, Kupffer cells of liver, lymph, alveoli, brain vessels mucous membranes.
Arises from the celiac axis of the abdominal aorta and travels laterally towards the left to supply the spleen with oxygen-rich blood.
Portion of the spleen located medially, is where the splenic arteries and veins enters and exits (gateway).
Lies in contact with stomach and tail of the pancreas.
Venous blood from spleen; running medially along the gastrointestinal ligament to its confluence with the SMV posterior to the neck of the pancreas to form the portial vein. (dumps into branches of the splenic vein)
15% composed of lymphatic tissue and follicles that surround the arterioles (and responsible for the production of antibodies; on paranchyma Splenic sinuses and splenic)
In the LUQ, Soft, sponge like organ, Largest mass of lymph, Highly vascular, asymmetric (variable in shape; generally ovoid w/ even borders, convex superior & concave inverior)
Spleen major functions
The four major function defense, hematopoiesis, RBS & platelet destruction.
Found in 10% of the general population. Usually less than 1 cm, more than 1 may be present, most often near the splenic hilum or attached to the tail of the pancreas. (80% lie in the hilum, 20% found in area of the pancreatic tail & in the messentary of the sm & lg intestins)
Congenital abnormality associated with congenital heart defect.
Most common splenic abnormality, usually due to complications of other diseases. Noted as a mass in the LUQ-may be due to recent trauma, portal venous congestion, systemic infection or a blood disorder such as anemia.
In the LUQ, Lies obliquely along the shaft of the 10th rib extending from the 8th to the 11th ribs.
Intraperitoneal between the fundus of the stomach of the and left helidiaphragm
Generally, comparable to the liver, homogenious, and low to mid echoes
Average length of spleen (varies w/ blood storage)
covered by connective tissue capsule, projection fibers (trabeculea) into its pulp, trabeculae divides spleen into communication compartments (filled with Wt. pulp & Red pulp)
Filter peripheral blood. Produces lymphocytes and plasma cells, prevents infection, destruction and removal of defective RBC's, stores iron & matabolites, pools platelets in high no.)