Viral Diseases of the Lower Respiratory System

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Created by:

TammyBLe  on May 16, 2011

Subjects:

microbiology lecture final

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Viral Diseases of the Lower Respiratory System

Respiratory Syncytial Virus
"RSV"
Children
1/7

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Respiratory Syncytial Virus "RSV"
Children
Influenza RNA virus
8 segments capable of reassembly
Complications: Reye's Syndrom
Transmitted by : Respiratory droplets, indirect contact, fomites.
Trivalent Vaccine
H Spike Hemmagglutinin
Binds to host cells
N Spike Neuraminidase
Assists in viral budding and release
Antigenic Variation New strains, new HN Spikes resulting in mutation and reassortment.
Type A : Most pandemics
Antigenic Drift minor mutations in genes that code for H&N Spikes.
Antigenic Shift Reassortment of RNA from different strains

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