Two parts of Blood
Plasma and cellular elements
Plasma accounts for how many percent of blood?
What are the components of plasma
Electrolytes, buffers, sugars, blood proteins, lipoproteins, CO2, O2, and metabolic waste products
What is the principal blood buffer
Normal blood pH
What are the blood proteins?
AFIL. Albumin, Fibrinogen, Immunoglobulins, and Lipoproteins. Most are made in the liver.
Essential for maintaining oncotic pressure, the osmotic pressure in capillaries due only to plasma proteins.
Essential for blood clotting
Large particles consisting of fats, cholesterol, and carrier proteins. They transport lipids in bloodstream.
buffer reaction in blood
CO2 + H2O = H2CO3 = HCO3- + H+
Principal waste product
Urea, a carrier excess of nitrogen. Bilirubin, a byproduct of heme
What are the cellular elements?
Eryhtrocytes, Leukocytes, Platelets. All formed from bone marrow stem cells (Megakaryocytes)
What hormone stimulates RBC production in bone marrow?
erythroprotein- made in kidneys
Where are old RBC eaten?
In the spleen and liver.
It is a cell without a nucleus or mitochondria.
Special attribute of RBC
it requires ATP energy for ion pumping and cell structure. RBC relies on glycolysis for ATP synthesis.
It has normal cell structure. It fights infection and dispose debris
Three types of Leukocytes
Monocytes, Lymphocytes, and Granulucytes
Macrophages: phagocytose debris and macroogranisms; amoeboid motility; chemotaxis
B-Cells and T Cells
What are B-cells?
B-cells : mature into plasma cells and produce antibodies.
What are T-cells
T-cells: kill virus infected cells, tumor cells and reject grafts
Neutrophil, Eosinophil, Basophil
Phagocytose bacteria resulting in pus; amobeoid motility, chemotaxis
Destroy parasites; allergic reactions
Store and release histamine; allergic reactions
Like RBC, it doesnt have nucleus. Function to aggregate site of damaged vessels forming a platelet plug
term for the body's mechanism of preventing bleeding
Also involved in hemostatic response. A threadlike protein which forms a mesh that holds the paltelet plug.
Fibrinogen is converted into Fibrin
Converts Fibrinogen into Fibrin. Needs help of Calcium and Vit K