lymphoid system and immunity - part 3

Created by eiserme 

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20 terms

desmosomes

typical cell-cell connection

diapedesis/emigration

the movement of immune cells out of the blood, across the capillary wall, and into the tissue; triggered by endothelial expression of cellular adhesion molecules (CAMs)

dolor

pain

eosinophils

attack parasites or other antibody-coated pathogens

epitope

a shape; the 3 dimensional structure of an amino acid sequence, carbohydrate, glycoprotein, or glycolipid

glucocorticoids

steroid hormones produced by the suprarenal gland that inhibit immune cell activity

graft rejection

immune response against transplanted tissues; T cell response to foreign Class I MHC proteins on donated cells

heavy chains and light chains

polypeptides that join together to form antibodies

helper T cell

lymphocyte that recognizes antigen and stimulates the activation of B cells and other T cells

histamine

chemical signal released by basophils and mast cells; induces vasodilation and increased capillary permeability

human immunodeficiency virus (HIV)

retrovirus that primarily attacks helper T cells; can lie dormant for years; is transmitted via close contact with body fluids, primarily blood, semen, and vaginal excretions

humoral immunity

antibody-mediated immunity; immune response that includes the antibodies that circulate in body fluids; requires a B cell response

IgA

immunoglobins found in secretions, including breast milk

IgD

immunoglobins expressed on the surface of B cells; binding of antigen to these sensitizes B cells

IgE

immunoglobins that bind basophils and mast cells and antigens simultaneously, stimulating the release of histamine; important component in the development of allergies

IgG

major class of immunoglobins; produced in the primary response and in large quantities in the secondary response to provide long term immunity; can cross the placenta providing passive immunity; anti-Rh antibodies are these, which can cause hemolytic disease of the newborn

IgM

first class of immunoglobins secreted during the primary response; circulate as clusters of 5 antibodies (wagon-wheel); responsible for agglutination during transfusion reactions of incompatible blood types; can bind bacteria

immunity

the ability to resist infection or disease due to the actions of the specific defenses

immunodeficiency disorder

failure of the immune system to develop properly or a defect in the immune system

immunoglobin

antibody

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