lymphoid system and immunity - part 3

Created by eiserme 

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20 terms


typical cell-cell connection


the movement of immune cells out of the blood, across the capillary wall, and into the tissue; triggered by endothelial expression of cellular adhesion molecules (CAMs)




attack parasites or other antibody-coated pathogens


a shape; the 3 dimensional structure of an amino acid sequence, carbohydrate, glycoprotein, or glycolipid


steroid hormones produced by the suprarenal gland that inhibit immune cell activity

graft rejection

immune response against transplanted tissues; T cell response to foreign Class I MHC proteins on donated cells

heavy chains and light chains

polypeptides that join together to form antibodies

helper T cell

lymphocyte that recognizes antigen and stimulates the activation of B cells and other T cells


chemical signal released by basophils and mast cells; induces vasodilation and increased capillary permeability

human immunodeficiency virus (HIV)

retrovirus that primarily attacks helper T cells; can lie dormant for years; is transmitted via close contact with body fluids, primarily blood, semen, and vaginal excretions

humoral immunity

antibody-mediated immunity; immune response that includes the antibodies that circulate in body fluids; requires a B cell response


immunoglobins found in secretions, including breast milk


immunoglobins expressed on the surface of B cells; binding of antigen to these sensitizes B cells


immunoglobins that bind basophils and mast cells and antigens simultaneously, stimulating the release of histamine; important component in the development of allergies


major class of immunoglobins; produced in the primary response and in large quantities in the secondary response to provide long term immunity; can cross the placenta providing passive immunity; anti-Rh antibodies are these, which can cause hemolytic disease of the newborn


first class of immunoglobins secreted during the primary response; circulate as clusters of 5 antibodies (wagon-wheel); responsible for agglutination during transfusion reactions of incompatible blood types; can bind bacteria


the ability to resist infection or disease due to the actions of the specific defenses

immunodeficiency disorder

failure of the immune system to develop properly or a defect in the immune system



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