Chapter 7: The Muscular System -Microscopic anatomy of skeleta muscle cells (myofibers):

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XKSIMON1X  on July 6, 2011

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module 7

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Describe

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Histology

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Chapter 7: The Muscular System -Microscopic anatomy of skeleta muscle cells (myofibers):

long cylindrical cell, 100um in length
Describe the microscopic anatomy of skeletal muscle cells (myofibers): General size and shape
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Definitions

long cylindrical cell, 100um in length Describe the microscopic anatomy of skeletal muscle cells (myofibers): General size and shape
found at periphery of cell and next to sarcolemma Describe the microscopic anatomy of skeletal muscle cells (myofibers): nuclei
plasma membrane of muscle cell Describe the microscopic anatomy of skeletal muscle cells (myofibers): sarcolemma
cytoplasm of muscle fiber Describe the microscopic anatomy of skeletal muscle cells (myofibers): sarcoplasma
oxygen binding protein in muscle fibers (oxygen stores) Describe the microscopic anatomy of skeletal muscle cells (myofibers): myoglobin
myofibers appear striated or striped due to the presence of I light bands where the thin filaments are located and A dark bands where they are thick and thin filaments Describe the microscopic anatomy of skeletal muscle cells (myofibers): striations
functional contractile unit of myofibril; one sarcomere consists of the filaments extending btwn Z discs Describe the microscopic anatomy of skeletal muscle cells (myofibers): sarcomere
(Z-disc) dense region separating sarcomeres Describe the microscopic anatomy of skeletal muscle cells (myofibers): Z-lines
the smaller structures (filaments) that make up the myofibril Describe the microscopic anatomy of skeletal muscle cells (myofibers): Myofilaments
thin filaments, thick filaments, elastic filaments What are the three types of myofilaments making up skeletal muscle?
diameter 8nm, composed of actin Define the thin filaments of skeletal muscle?
diameter 16nm, composed of myosin Define the thick filaments of skeletal muscle?
composed of titin, anchors thick filaments to Z discs to stabilize the relaxed state of the sarcomere. Define the elastic filaments of skeletal muscle?
troponin and tropomyosin Describe the microscopic anatomy of skeletal muscle cells (myofibers): Regulatory proteins
contractile protein in thick filament, shaped like two golf clubs twisted together Describe the microscopic anatomy of skeletal muscle cells (myofibers): Myosin
myosin head that extends to the thin filaments (head of golf club) Describe the microscopic anatomy of skeletal muscle cells (myofibers): crossbridge
contractile protein in thin filament, globular actin molecules join to form a helix Describe the microscopic anatomy of skeletal muscle cells (myofibers): actin
regulatory protein on thin filament Describe the microscopic anatomy of skeletal muscle cells (myofibers): tropomyosin
regulatory protein on thin filament Describe the microscopic anatomy of skeletal muscle cells (myofibers): troponin
are located on each actin molecule so actin can interact with myosin during contraction Describe the microscopic anatomy of skeletal muscle cells (myofibers): myosin binding sites
stores Ca2+ Describe the microscopic anatomy of skeletal muscle cells (myofibers): Sarcoplasmic reticulum
carry nerve stimulus (action potential) from outside of deep fiber into the muscle cell Describe the microscopic anatomy of skeletal muscle cells (myofibers): Transverse tubules

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