Diuretics MOA
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Created by:
chermainekelly Plus on July 8, 2011
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7 terms
Terms | Definitions |
|---|---|
 Osmotics: proximal tubule | decrease sodium and water reabsorption |
| osmotics: loop of henle | increases medullary blood flow to decrease medullary hypertonicity and reduce sodium and water reabsorption |
| osmotics: collecting tubule | sodium and water reabsorption decreases because of reduced medullary hypertonicity and elevated urinary flow rate |
| carbonic anhydrase inhibitors: proximal convoluted tubule | inhibition of renal carbonic anhydrase decrease sodum bicarbonate reabsorption |
| thiazides and thiazide-like | inhibition of Na+/Cl- symporter |
| loop or high-ceiling | inhibition of the luminal Na+/K+/2Cl- transport system |
| potassium-sparing | inhibition of sodium and water reabsorption by: competitive inhibition of aldosterone; blockade of sodium channel at the luminal membrane |
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