Nervous System

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mcampisi  on July 9, 2011

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Nervous System

Three overlapping functions
sensory input; integration; motor output
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Three overlapping functions sensory input; integration; motor output
Sensory input gathered information and monitoring stimuli
Integration processes and interprets the sensory input and then decides what needs to be done
Motor Output the response to stimuli that is carried out by effector organs
Brain and Spinal Cord CNS; integration and command center
Spinal nerves paired nerves that carry impulses to and away from the spinal cord
PNS peripheral nervous system; links all parts of the body to CNS
Cranial nerves paired nerves that carry impulses to and from the brain
Afferent Division conveys impulses to CNS
Somatic afferent fibers from skin, muscles, joints
Visceral afferent fibers from visceral organs of ventral body cavity
Efferent division transmits impulses from CNS to effector organs-muscles and glands
Somatic Nervous system voluntary nervous system
Autonomic Nervous system involuntary nervous system
Sympathetic Division mobilizes body systems during activity
Parasympathetic Divison conserves energy
neurons nerve cells that transmit electrical signals
Neuroglia supporting cells; smaller cells that surround nuerons
Four types of neuroglia in CNS astrocytes, microglia, oligodendrocytes, ependymal cells
Astrocytes most abundant and versatile
Microglia transform into macrophage to ingest debris/microorganisms; denies immune system access to CNS
Oligodendrocytes form insulation called myelin sheath around thicker neurons
Ependymal Cells line brain cavity to keep barrier between cerebrospinal fluid and the tissue fluid bathing cns cells
Two types of neuroglia in PNS satellite cells; schwann cells
Satellite Cells surround the cell bodies in PNS
Schwann cells form myelin sheath in PNS
Characteristics of Neurons conduct electrical nerve impulses; extreme longevity; amitotic; high metabolic rate
Plasma Membrane of a Neuron site of electrical signaling and plays a part in cell to cell interactions during development
Neuron Cell body most cell bodies are in the CNS
Dendrites main receptive or input region; receives input from other neurons; conveys incoming messages towards the cell body
Axons conducting region of the neuron; generates nerve impulse called an action potential and transmits them away from the body
Axons in the CNS myelin sheath is formed by oligodendrocytes; no neurilemma; nodes of ranvier more widespread
White matter mylinated fibers
Gray matter cell bodies and unmylenated fibers
Myelin whitish fatty tissue that covers long or large axons-does not cover dendrites
Myelinated fibers conduct impulses rapidly
Functions of Myelin protects and insulates axon fibers; increases speed of impulse transmission
Neurilemma outermost layer of schwann cell
Nodes of Ranvier gaps in myelin sheath
Unmyelinated fibers covered by schwann cell but they are not coiled and do not forma myelin sheath
Multipolar neurons most common type; major type in CNS
Sensory neurons transmit impulses toward the CNS (afferent)
Motor neurons transmit impulses away from the CNS (efferent)
Action potentials nerve impulses; electrical impulses carried along the length of the axons; the underlying functional feature of the nervous system
Cause of Action Potentials flow of ions across cellular membranes to cause electric current
Passsive or leakage membrane ion channel always open
Chemically gated membrane ion channel open with binding of specific neurotransmitter
Voltage gated channels open and close in response to membrane potential
Mechanically gated channels open and close in response to physical deformation of receptors
Potassium plays the most important role in generating the membrane potential
Membrane potential voltage across the membrane; cytosol has increased concentrations K ions than Na ions and there is a greater concentration of Na ions in extracellular fluid
Graded Potentials short lived changes in membrane potential; sufficiently strong graded potentials can initiate action potentials and are critical to generation of action potentials
Axon hillock where transition from graded to action potential takes place
Action Potentials the principal means of neural communication
Nerve impulse an action potential in the axon of a neuron
Four Stages of AP generation Resting; Depolarization; Repolarization; Hyperpolarization
Resting State All gated Na and K channels are closed; Na activation gates closed; inactivation gates open
Depolarization Phase Na channels open
Repolarization Na channels inactivating; K channels open; restores the resting electrical conditions of the neuron
Hyperpolarization K channels remain open; Na channels resettling
continuous conduction unmyelinated fibers; action potentials are generated at sites next to each other and conduction is relatively slow
salutatory conduction myelinated fibers; action fibers are triggered only at the nodes and jump from one mode to the next
Threshold a value depolarization must reach to generate an action potential
All or none phenomenon action potentials either happen completely or not at all
absolute refractory period enforces one way transmission of nerve impulses; A period of time following an action potential during which no additional action potential can be evoked regardless of the level of stimulation
relative refractory period a period after firing when a neuron is returning to its normal polarize state and will only fire again if the incoming message (impulse) is stronger than usual; returning to arresting state
Synapses a junction between neurons that mediates information transfer from one neuron to another neuron or to an effector cell
Electrical Synapses less common than chemical synapses; ions flow directly from neuron to neuron; important in the CNS for arousal from sleep, mental attention, emotions, and memory
Chemical Synapses specialized for the release and reception of neurotransmitters
Synaptic Cleft fluid filled space separating presynaptic and postsynaptic neurons
Synaptic delay time needed for neurotransmitter to be released, diffuse across the synapse, and bind to receptors
Excitatory postsynaptic potentials (EPSP) graded potentials that can initiate an action potential in an axon; a singly EPSP can not induce an action potential; they must summate temporally or spatially to induce an AP
Inhibitory postsynaptic potentials (IPSPs) graded post-synaptic hyperpolarizations, which decrease the likelihood that an action potential will be generated
Acetycholine released at neuromuscular junction; released by all neurons that stimulate skeletal muscle; associated with voluntary movement
Biogenic Amines plays a role in emotional behaviors and our biological clock
Excitatory neurotransmitters cause depolarizations
Inhibitory neurotransmitters cause hyperpolarizations
Channel linked receptors mediate direct neurotransmitter action; very quick
G Protein linked receptors responses are indirect, slow, complex, prolonged, and often diffuse
Neural Pools functional groups of neurons that integrate incoming information and forward the processed information to its appropriate destination
Divergent circuit one incoming fiber stimulates ever increasing number of fibers often amplifying circuits
Convergent Circuits opposite of divergent circuits; resulting in either strong stimulation or inhibit
Reverberating chain of neurons containing collateral synapses with previous neurons in chain
Parallel after-discharge incoming neurons stimulate several neurons
Serial Processing input travels along one pathway to a specific destination
Parallel Processing input travels along several pathways

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