TIVA/CRI
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10 terms
Terms | Definitions |
|---|---|
 Which agents are suitable for TIVA? | thipentone, ketamine, saffan (cats only), Alfaxan CD, Propofol |
| Thipentone | cumulative, anti-analgesic |
| ketamine | (relatively) cumulative, side effects |
| Aflaxan CD | rapid clearance, minimal accumulation |
| Propofol | rapid clearance and recovery predictable metabolism minimal accumulation little hangover effect poor reflex suppressant need additional analgesia |
| Intermittent bolus | okay for very short cases (<5 min) poor quality (peaks and troughs) large total drug dose slow recovery |
| Constant rate infusion | Smoother anesthesia become deeper with time Risk of awareness or side effects |
| Variable rate infusion | Smoother lower total drug dose faster recovery frequent adjustment needed |
| Target controlled infusion | Achieves stable plasma concentration simple to use easy to change in response to clinical effect rapid control of depth |
| Analgesics to use with propofol | MORPHINE AND PETHIDINE: difficult to titrate to effect, active metabolites, limited potency FETANYL: 100x morphine potency, 20-30 min clinical effect ALFENTANIL: 20x morphine potency, 5 min clinical effect, bradycardia REMlFENTANIL: 100x morphine potency, 3-5 min clinical effect |
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