What is the doc for gas gangene (clostridium Perfringen)
however if you had a patient allergic to penicillin G - then you you would use a 1st generation cephalosporin like cefazolin
What is the DOC for syphilis? (treponema pallidum)
however if you had a patient allergic to penicillin G - then you would use a first generation cephalozporin like cefazolin or cephalexin
Which is more acid stable - penicillin G or Penicillin VK?
Penicillin VK - more acid stable so taken orally but poor bioavailbability.
Would you give depot penicillin for syphillis
yes it is DOC
what are nafcillin, oxacillin and dicloxacillin used for?
What antistaphylococcl penicillins but these are used for serious sysstemic staphylococcal infections such as bacteremia, endocarditis, meningitis, respiratory tract infections
What is the mode of administration for oxacillin/nafcillin/dicloxacillin
Oxacillin and nafcillin - intermittent i.v. infusion
oxacillin/dicloxacillin - can be given orally
How is amoxicillin taken?
amoxicillin is given orally
What is amoxicillin used for?
Surigical pretreatment in patients with atypical heart valves undergoing oral surgery (prophylaxis of endocarditis)
What is Ampicllin DOC for?
What is the first line agent for treating pseudomonas aeruginosa
Ticarcillin/potassium clavulanate (timentin)
3rd generation cephalosporin - Ceftazidime
4th generation cephalosporin - cefepime
what are the three things that all cephlasporins are active against?
staphylococci, and pneumococci and streptococci
How would you treat pneumonia and urinary tract infection that is causd by klebsiella pneumoniae?
What will you never use cephalosporin [1-4] against?
Methicillin-resistant staphyloccosus aureus
What can you use 5th generation cephalosporin against?
MRSA, VRSA, VISA and enterococcus faecalis
it will also not work against clostridium deficile and listeria monocytogenes
what are the three first generation first generation cephalosporins?
lex zol and drox
What would use cefazolin for?
DOC for surgical prophylaxis
Wha would you use for an infection of bacteroides?
Cefoxitin is the first line agent
bacterioides causes a mixed anaerobe infection like diverticulitis and peritonitis
What are the third genreation cephalosporins?
tiz taz Tri fixime dinir but pod dit tax
which of the 3rd generation cephalosporin drugs ccross the blood-brain barrier?
ceftriaxone, cefotaxime, ceftazidime and ceftizoxime
How would you treat neisseria gonorrhoeae
3r generation cephalosporin - ceftriaxone - first line agent
3rd generation cephalosporin - cefixime
which of the following cephalosporins would you use against meningitis caused by haemophilus influenzae?/
ceftriaxone - first line agent
cefotaxime - first line agent
What would you use against streptococccus pneumonia that is penicillin resistant
first line agent - ceftriaxone
first line agent - cefotaxime
what would you use as a first line agent for typhoid fever de to salmonella
Which of the cephalosporins are availalbe fororal administration?
cephalexin, cefadroxil, cefprozil, cefuroxime axetil, cefaclor, cefdinir, cefixime, cefibuten, cefpodxime, cefditoren
What would you use to treat nenonatal and childhood meningitis caused by haemophilius influenzae?
DOc - ceftriaxone or cefotaxime
which drug prolongs the activity of cephalosporins eliminated by tubular secretion
Which drug is predominantly excreted via the bile and employed in patients with decreased renal function?
Would you use cephalosporins on a patient allergic to penicillins>
no cause of immediate hypersensitivity reation to penicillins
what are uou afraid of with cephalosporins?
disulfiram-like reaactions in the case of cefotetan
what are the carbapenems?
carbapenems =synthetic b-lactam antimicrobials
what would you use carbapenems for?
how are carbapenems administered?
I.V. or Intra muscularly
How are carbapenems exreted?
why would use monobactam oveer other penicillins/cephalosporins?
if a patient is allergic to penicillins and comes in with infection of
gram negative bacilli such as pseudomonoas and serratia
- also works against proteus mirabilis, e. coli, klebsilla pneumoniae, neisseria, enterboacter, haemophilus influenzae, moraxella catarrhalis, pasteurella, citrobacter
you would use monobactam