Patho exam 3 respiratory
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84 terms
Terms | Definitions |
|---|---|
What are the primary symptoms of respiratory disease? | Cough, fever, dyspnea, sputum |
When used for diagnosing, what does sputum signal? | Denotes airway disease unless lung abcess. Also seen in asthma, bronchitis, or bronchiectasis |
What information is needed to solve the problem of diagnosis? | OnsetAcute/subacute Exacerbation of existing disease Slow progressing disease Pain Risk factors Chest X-ray |
What are possible upper respiratory tract infections? | Allergic rhinitisPharyngitis Laryngitis Sinusitis |
What are the signs and symptoms of rhinitis? | Nasal turbinates, erythema, swelling, exudate |
What is the etiology of rhinitis? | Viral, bacterial, antigenic, hormonal (premarin/progesterone) |
What is the etiology of sinusitis? | Viral, bacterial, antigenic, immunogenic, hyperplasia |
What are the signs and symptoms of sinusitis? | Nasal turbinates, erythema, swelling, yellow to green educate, pain in sinuses with palladium, sinus swelling |
What is the treatment of rhinitis? | Antihistamines, topical steroids, leukotriene receptor antagonist, expectorants |
What is the treatment of sinusitis? | Antihistamines, anti-inflammatories, antibiotics, expectorants |
What is the etiology of laryngitis? | Viral, bacterial, inflammation, infection, hyperplasia, dysplasia |
How is laryngitis diagnosed? | Auditory hoarseness, laryngoscopy, ct imaging |
How is laryngitis treated? | Supportive, ENT specialist care, rest larynx no talking |
What is the etiology of pharyngitis? | Post nasal drainage(vesicles/cobblestone appearance), viral, bacterial (group a beta hemolytic strep or other pathogens) |
What are the signs and symptoms of pharyngitis? | Erythema, mid to posterior pharyngeal abcess swelling, pain, exudate in tonsils and posterior pharynx |
What is the treatment for pharyngitis? | Bacterial source- microbialViral or post nasal drainage- supportive and treatment of sinusitis(antihistamines, anti-inflammatory, expectorants) |
What are the possible lower respiratory tract diseases? | Pleural abnormalitiesPulmonary emboli COPD bronchitis Asthma ARDS Infections- pneumonia, lung abcess, tuberculosis Lung cancer |
What is the purpose of the pulmonary circuit in circulation? | Facilitate gas exchangeDeliver nutrients Reservoir for left ventricle Filtering system |
What is the difference I. Pressure between the pulmonary circuit and systemic circuit? | The pulmonary circuit has less pressure and resistance |
What are possible responses to irritants in the airways? | Cough, bronchoconstriction, increased ventilatory rate |
What does the Hering-Breuer expiratory reflex control? | Decreases ventilatory rate and volume |
What occurs when the j-receptors(juxtapulomnary capillary receptors) are initiated? | Sensitive to increased pulmonary capillary pressureInitiates rapid, shallow breathing Hypotension Bradycardia |
What should be monitored with initiation of the j receptors? | pH, PaCo |
What are the different types of pneumonthorax? | Open, tension, spontaneous, secondary |
What occurs in an open pneumonthorax ? | Communication with atmospheric pressure |
What occurs in a tension pneumothorax? | Site acts as a one way valve and air enters but cannot escape? |
What occurs in a spontaneous pneumothorax ? | Rupture of blend on visceral pleura, usually |
What occurs in a secondary pneumothorax? | Chest trauma, disease, mechanical ventilation |
What are the signs and symptoms of a pneumothorax? | DyspneaPleural pain Tachypnea Possible compression atelectasis Possible displacement of medistinal contents |
How is a pneumothorax diagnosed? | Chest X-ray for air in apex of lungAuscultation |
What is the treatment of a pneumothorax? | Remove air/blood from parietal/visceral spaceRe-expand lung with chest tubes |
What are the possible etiologies of a pulmonary emboli? | Fat thrombusAir |
What is the manifestation of a pulmonary emboli? | Ischemia of all tissue distal to supporting vasculatureHypoxic vasoconstriction |
What are the signs and symptoms of a pulmonary emboli? | patient can be asymptomatic, SOB, chest pain, tachypnes, V/Q Imbalances, low PaCO2, low PaO2, pulmonary hypertension, decreased cardiac output, systemic hypotension, shock |
How is pulmonary emboli diagnosed? | pulse ox, chest x-ray, VQ Scan showing ventilation but no perfusion, CT scan, D-Dimer, MRI |
What is the treatment for pulmonary emboli? | prevention, supportive O2, anticoagulants |
What is atelectasis? | Inadequate aveolar filling where air is replaced by fluid |
What is flail chest? | hole in pleural space |
What is pleural effusion? | fluid in pleural space which can lead to ateclectasis or displaced mediastinal contents |
What is Pleurisy? | inflammation between parietal and visceral pleura |
What is Costochondritis? | Inflammation between ribs in intercostal spacesIs the most common cause of chest pain in children |
What is an Empyema? | Infection in pleural space |
Pulmonary Edema | ... |
What is pneumoconiosis? | Inhalation of inorganic dust particles |
How does pneumoconiosis manifest? | Pulmonary fibrosis |
What is the etiology of pneumononiosis? | idiopathic, result of inflammatory process after exposure to antigen/immunogen |
What is the symptom of pneumoniosis? | decreased lung compliance |
What is the etiology of Adult Respiratory Distress Syndrome? | SepsisMultiple Trauma DIC, smoke |
What are the manifestations of ARDS? | Inflammation, diffuse aveolo-capillary injury leading to increased capillary permeability causing pulmonary edema, hyaline membrane form, fibrosis, decreased FRC |
What is the etiology of Asthma? | inflammationBroncho-constriction Hyper-responsivity to co-morbid allergies |
What symptoms classify Mild Intermittent Asthma? | Symptoms 2/wk or 2/night/month Peak flows greater than or equal to 80% of your personal best, with less than 20% variability in daily peak flow measurements |
What symptoms classify mild persistent asthma? | more than 2/wk but less than 1/day or 2/night/month |
What symptoms classify moderate persistent asthma? | daily symptoms or more than 1/night/wkPeak flows that are 60 to 80% of personal best, or more than 30% variability in daily peak flow measurements |
What symptoms classify severe persistent asthma? | Continual symptoms with peak flows that are less than or equal to 60% of personal best, or more than 30% variability in daily peak flow measurements |
What are the medications used to treat asthma? | Mucolytics, Antihistamines, Bronchodialators, antiinflammatories, leukotriene receptor antagonist |
What are the goals of treatment for asthma? | minimal or no chronic symptomsminimal or no exacerbations no limitations on activities peak flows greater than 80% of personal best minimal or no adverse effects from medications |
What is COPD? | Chronic, irreversible pathologic lung changes |
What is primary emphysema? | Deficiency of alpha 1 antitrypsin which inhibits the action of prteolytic enzymes |
What is secondary emphysema? | Deficiency of alpha 1 antitrypsin by smoking because of excessive neutrophils in the lungsParenchyma releases prtolytic enzymes that damage respiratory bronchioles and alveolar walls |
What occurs in emphysema? | destruction of aveolar septaelimination of portions of capillary bed Increases volume of air in acinus Loss of elastic recoil causes expiratory difficulty Hyperinflation of aveoli Bronchoconstriction |
What are the clinical manifestations of Emphysema? | exertional dyspnea progressing to resting dyspneano cough in beginning little sputum production thin body tachypnea with prolonged expiration use of accessory muscles AP diameter increased Hyper-resonance with percussion Orthopnea |
How is emphysema diagnosed? | Chest X-Ray showing flat diaphragm, transulucent and overdistended lung fieldsPFT's- decreased FVC FEVI, increased FRC, RV, and TLC |
What is the treatment for emphysema? | BronchodialatorsMucolytics Anticholinergics Antihistamines Oxygen Removal of irritant Relaxation exercises Reconditioning exercises Avoiud URI's |
WHat is the disease progression of emphysema? | usually accompanied with chronic bronchitisIncreased number of infections Increased dyspnea Cor pulmonale Death |
What is the etiology of pneumonia? | Organisms |
What are the manifestations of pneumonia? | inflammatory and immune response result in deposits of fibrin on pleural surfaces, consolidation of lung parenchyma |
70% of all cases of pneumonia are | Community Acquired |
What is hospital acquired pneumonia likely to cause? | residual lung sequellae like lung abcess or emphyema |
What are the likely causes of exposure to the organisms causign pneumonia? | inspiration of infected dropletsPorr dental hygeine causes normal flora to become pathogenic Septicemia IV drug abuse |
How is pneumonia diagnosed? | Chest Xray shows infiltratesColor of sputum (rusty streptococcus, salmon pinkl staphylococcus, green pseudomonial) Amount of sputum (Myoplasma and viral have scant sputum) Culture and sensitivity of sputum |
What are the clinical manifestations of pneumonia? | chillsfever productive or dry cough malaise pleural pain dyspnea hemoptysis |
What is the treatment for pneumonia? | Antibioticsmucolytics supportive oxgen |
What isthe criteria for hospitalization for pneumonia? | Any 3 of:resp rate >30 confusion/disorientation uremia, BUN >20 Leukopenia, WBC <20,000 Systolic <90 Multilobar infiltrates PaO2/FiO2 ratio <250 Thrombocytopenia, plt <100,000 Hypothermia <36C Hypotension requiring agressive fluid rescucitation |
What is the etiology of Tuberculosis? | Mycobacterium tuberculosis |
How is Tuberculosis transmitted? | Aireborn droplet or tissue contamination |
What is the patho of tuberculosis? | inflammatory response engulfs bacilli in granuloma or tubercle which causes a decreased function on lung parenchymaPhagocytosis breaks down granuloma releasing new bacilli |
What are the clinical manifestations of tuberculosis? | cough, progressivenight sweats purulent sputum hypoxemia fever anorexia/weight loss erosion of tubercle into parenchyma and possibly vessels |
How is tuberculosis diagnosed? | skin test (BCG immunization can cause false positive)chest x-ray sputum culture |
What is the treatment for tuberculosis? | Appropriate antimicrobialsProtect immune compromised |
What is the etiology of ung cancer? | TobaccosGenes Environment |
What are the different types of lung cancer? | SquamousSmall cell Adenocarcinoma Large Cell |
What are the clinical manifestations of lung cancer? | chronic coughpersistent infections airway obstruction hemoptysis pleural effusions |
How is lung cancer diagnosed? | Chest X-Ray biopsy Ct Scan |
What is the usual treatment for lung cancer? | ChemotherapyRadiation Surgery |
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