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5 Written Questions

5 Matching Questions

  1. Norepi incr inward Ca2+ during plateau via beta-1 receptors. It also incr SR Ca2+ pump activity by ___, which incr Ca2+ in SR.
  2. In working myoctes, phase 2 of AP is plateau caused by ___.
  3. PS (ACh) via muscarinic receptors decr atrial contractility by ___.
  4. In nodal pacing myocytes, phase 2 of AP is ___.
  5. In working myoctes, phase 3 of AP is rapid repol caused by ___.
  1. a absent
  2. b • transient incr I(Ca2+)- inward
    • incr K+ out
  3. c • 1º incr K+ out
    • decr Ca2+ in
  4. d decr inward Ca2+ current in plateau
  5. e phosphorylation of phospholamban

5 Multiple Choice Questions

  1. incr dev't tension
  2. • incr K+ conductance- outward
  3. decr rt of phase 4 depol in pacemaker cells
  4. EDV/RAP and CO/SV
  5. • positive chronotropy
    • pos dromotropy
    • pos inotropy

5 True/False Questions

  1. Muscarinic receptor activation causes ___ in the CV system.skin, splanchnic, and skeletal vascular smooth muscle constriction

          

  2. In nodal pacing myocytes, phase 1 of AP is ___.absent

          

  3. Digitalis has a pos inotropic effect. It inhibits ___ on the myocardial cell membrane.diminishing Na+ gradient, which diminishes Na+-Ca2+ exchange

          

  4. In nodal pacing myocytes, phase 0 of AP is upstroke caused by ___• incr Ca2+ conductance- inward
    • note that this is different; I(Na) in working myocytes

          

  5. In working myoctes, phase 4 of AP is resting membrane potential maintained by ___.I(K1)

          

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