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5 Written Questions

5 Matching Questions

  1. Norepi incr inward Ca2+ during plateau via beta-1 receptors. It also incr SR Ca2+ pump activity by ___, which incr Ca2+ in SR.
  2. Digitalis has a pos inotropic effect. It inhibits ___ on the myocardial cell membrane.
  3. I(f) is turned on by ___.
  4. In nodal pacing myocytes, phase 4 is slow repol (diastolic depol) caused by ___.
  5. PS (ACh) via muscarinic receptors decr atrial contractility by ___.
  1. a phosphorylation of phospholamban
  2. b Na+, K+ -ATPase (causing incr [Na+](intracel))
  3. c • I(f)- inward Na+
  4. d decr inward Ca2+ current in plateau
  5. e repol of memb potential in preceding AP.

5 Multiple Choice Questions

  1. incr dev't tension
  2. diminishing Na+ gradient, which diminishes Na+-Ca2+ exchange
  3. vagal
  4. • incr Ca2+ conductance- inward
    • note that this is different; I(Na) in working myocytes
  5. • transient incr I(Ca2+)- inward
    • incr K+ out

5 True/False Questions

  1. In working myoctes, phase 4 of AP is resting membrane potential maintained by ___.I(K1)


  2. Muscarinic receptor activation causes ___ in the CV system.• neg chronotropy
    • neg dromotropy
    • decr atrial inotropy


  3. In working myoctes, phase 1 of AP is initial repol caused by ___.• I(to)- transient K+ out
    • decr I(Na)


  4. In other words, Frank-Starling describes a proportional relationship between ___EDV/RAP and CO/SV


  5. Neg chronotropy reduces HR by ___.repol of memb potential in preceding AP.


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