Tricyclic Antidepressants DEPRESSION
|Tricyclic Antidepressants, TCAs||- are the oldest class of medication used in treatment of depression. All TCAs produce similiar effects and side effects. TCAs work by producing a non-specific blockade of the re uptake monoamine neurotransmitters NE and 5-HT. Lipophilic. Maximum antidepressnt effect may take up to 6 weeks to be achieved.|
|Tricyclic Auxillary Labels|| May cause drowsiness, alcohol may intensify this effect.|
May impair ability to drive.
Do not discontinue without medical supervision.
Avoid prolonged exposure to sunlight.
May discolour urine. Blue green - amitriptyline
|amitriptyline (antidepressant)||Levate (TCA)|
|desipramine (antidepressant)||Norpramin (TCA)|
|doxepin (antidepressant)||Sinequan, Zonalon (TCA)|
|imipramine (antidepressant)||Tofranil (TCA)|
|nortryptyline (antidepressant)||Aventyl (TCA)|
|trimipramine (antidepressant)||Surmontil (TCA)|