Pharm test 4 drugs
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Created by:
rachelcathey22 on July 24, 2011
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23 terms
Terms | Definitions |
|---|---|
Erythromycin | Broad spectrum antibiotic. Good for ppl allergic to penicillin. Give slow in IV. Safe, little ADEs except epigastric pain. Increase half-life of Warfarin |
Isoniazid | Treatment of TB; inhibits growth. ADEs are peripheral neuropathy and hepatitis. |
Rifampin | First line drug for TB. Destroys bacteria. Discolor body fluids. Can't give with HIV drugs. Lots of drug interactions |
Pyridium | Treats urinary pain. Discolors urine orange/red. Doesn't have antibacterial activity but makes symptoms of UTI better |
Acyclovir | For herpex and shingles. Can cause reversible nephrotoxicity (increased BUN and CK); neurotoxic esp in dialysis pts. Wear gloves. Safe during pregnancy |
NasalCrom | Mast cell stabilizer for allergic rhinitis. Best for prevention and takes a week or 2 to work. Not used for urgent need. |
Sudafed | Help with stuffiness in allergic rhinitis. Activates alpha1 adrenergic receptors to vasoconstrict-->reduce blood flow to nose-->reduce swelling. SNS stimulant (hyper states) |
Atrovent | Used to improve lung function through bronchodilation. Approved for COPD and used off label for asthma maintenance. Decreases mucous production. Will not provide rescue relief |
Robitussin | Suppresses cough reflex by elevating CNS threshold. Opioid derivative. Avoid in pts that need cough reflex. Subject to abuse |
Guifenesin/Mucinex | Relief of resp conditions that have a dry, nonproductive cough. Produces more productive cough. Decreases viscocity. Teach pts if cough lasts >7 days see dr |
Acetylcysteine/Mucomyst | Breaks up thick tenacious sputum-->watery. Rotten egg smell. Antidote for tylenol. Works fast as nebulizer. Not given in pts with esophageal varices, PUD. Causes burning in upper airway |
Inhaled Cromolyn Sodium | Asthma anti-inflammatory drug. Safest of all asthma meds. Tolerance doesn't develop. Works on mast cells-prevent from degranulation. Take daily even if ok. Not for acute attack. Can be taken 15 min before x for x-induced asthma |
Albuterol/Proventil | Rapid acting Beta 2 agonist used as rescue drug for acute asthma. Short acting. Promotes bronchodilation. Combo therapy best way to go with asthma pts. Mild systemic effects (Hyper) |
Servent | Long acting beta 2 agonist for maintenance of asthma. In dry powder form. Not first line drug and don't take a monotherapy-not effective (need combo). |
Theophylline | First line asthma maintenance drug-decreased in use due to new safer drugs. CNS stimulation. Narrow therapeutic range (10-20) |
Epoetin alfa | Treatment of anemia assoc w/ acute renal failure. ^ RBC production. Can cause hyper states; can lead to anaphylaxis. Get baseline Hgb twice a week until target met. Too high-cardio risk. Don't shake |
Neumega | Prevention of severe thrombocytopenia and reduce need for platelet transfusions in cancer pts. Can have severe allergic reaction(anaphylaxis); don't give to pts with HF. Don't shake. |
Sandimmune | Adjunct treatment to prevent transplant rejections-prevent graft vs host disease. Can cause nephro and hepatotoxicity. Monitor blood tests. High fat diet in hospital; low fat diet at home. |
Prednisone | Anti-inflammatory, anti-allergies, immunosuppressant, inhaled for mod/severe asthma. Osteoporosis with long term use. Caution in DM-watch blood sugars. Taper off. Take with milk or food |
Prilosec | PPI-Treat PUD (H Pylori in combo w/ antibiotics); GERD. Effects persist til new enzymes produced. ^ risk of pneumonia with ^ gastric pH. Take just before eating. Don't crush/chew |
Zantac | Treat active duodenal or benign ulcers; GERD. With or w/o food. Blocks histamine action to inhibit gastric acid secretion. Smoking dec efficacy. Monitor trough levels in renal/liver pts before giving dose; pH/pneumonia; GI bleeding |
Reglan | Diabetic gastroparesis; GERD; prevent N/V post op during chemo. Increases peristalsis and tone-->gastric emptying. Can cause sedation, diarrhea; EPS side effects can happen |
Lomotil (Diphenoxylate HCL w/ Atropine) | For diarrhea only. Similar to narcotic so atropine given to make people not want to take in excess. Slows motility, prolong transit time so stool more formed |
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