BCS 110 - Lecture #15 Learning & Memory-Neuropsychology

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abbyt  on December 15, 2008

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BCS 110 - Lecture #15 Learning & Memory-Neuropsychology

Pavlov
Who did Classical Conditioning?
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Pavlov Who did Classical Conditioning?
Conditioned stimulus (metronome) with unconditioned stimulus (meat)=unconditioned response (salivation), ?=conditioned response (salivation) What is Classical Conditioning?
Skinner Who did Operant Conditioning?
Reinforcement & punishment What is Operant Conditioning?
AKA working memory, kind of like RAM in computer, something used for a particular task for about 2 minutes, store information for short term use (1s to 2-3mn); Phonological loop & Visuospatial sketchpad What is Short-Term Memory?
Type of short-term memory, 7+/-2 items What is a Phonological Loop?
Type of short-term memory, 4+/-2 items What is a Visuospatial Sketchpad?
Entorhinal Parahippocampal Cortex, Hippocampus, Amygdala (plays a role in memory, though minor-mostly involved in control of emotion), Cortex (big role in memory), and Dorsomedial Thalamus What areas of the brain play a role in Long-Term Memory?
HM had massive episelpsy-had epileptic fits all the time, he had part of the temporal lobes (hippocampus & surrounding cortex) removed on both sides in an attempt to cure epilepsy, removed a piece of cortex, never had epileptic fits after that day but had no way of sotring new memories Who was HM?
A patient who had similar epilepsy problems to HM, but due to a virus Who was RB?
Mild retrograde amnesia (two years prior to the surgery were lost), very severe anterograde amnesia (he cannot learn a new fact--> declarative memory--facts), intact short-term memory, normal IQ, he is still able to learn new skills even though he is unaware of it (procedural memory-skills like skiing & riding a bike), towers of hanoi What were HM's Symptoms post-surgery?
Two years prior to accident/illness lost What is Retrograde Amnesia
Cannot learn new facts What is Anterograde Amnesia?
Facts What is Declarative Memory?
Skills like riding a bike & skiing What is Procedural Memory?
Long-term memory loss (not short term as claimed in them movie), like many patients-he is aware of his deficit What type of Memory Deficit does the main character have in Memento?
2 patterns--> well underneath the pattern & has to remember which one has food underneath it What is a Delayed Non-Matching-to-Sample Task?
Hippocampus + surrounding cortex, PREFRONTAL CORTEX What areas of the brain are for Short-Term Memory?
Hippocampus & surrounding cortex & the cortex/entorhinal parahippocampal cortex, Thalamic Structures (dorsomedial thalamus, dorsomedial nucleus of the thalamus), & amygdala What other areas of the brain play a role in Long-Term Memory?
Hippocampal lesions in rats affect performance in the radial maze & the morris search task What is Spatial Memory?
Place cells What type of cell does the Hippocampus contain?
Stores long-term memories that are more than 2 years old, HM--hippocampus was gone, but the cortex was still intact-he had a great memory of anything that happened 2 years prior to the surgery What is the Cortex's role in Long-Term Memory?
Severe lesions in the entorhinal cortex, basal forebrain (acetylcholine) and throughout cortex (due to amyloid deposit), declarative memory most affected (but they can learn new skills), retrograde & anterograde amnesia (unlike HM), many other cognitive functions affected as well, the cortex is affected What is Alzheimer's Disease?
projects to the prefrontal cortex (assoiated with short-term memory) What does the Dorsomedial Thalamus do?
Thiamine deficiency (needed to metabolize glucose), seen more in alcoholics, thalamus affected, normal on non-declarative tasks such as word completion tasks, confabulation What is Korsakoff's Syndrome?
Retrograde & Anterograde Amnesia, problems with recalling temporal order (typical of prefrontal patients) What types of memory are affected by Korsakoff's Syndrome?
Seen with Korsakoff's patients, known for making up stories What is Confabulation?
Amygdala involved in emotion-if you lose it, you lose this boost of learning you get with strong emotions, events associated with strong emotions are remembered better (epinephrine) What does the Amygdala do with Long-Term Memory?
Declarative & Non-declarative (skills/procedural) What are the tpyes of Long-Term Memory?
Explicit Is Declarative Memory implicit or explicit?
Implicit Is Non-declarative Memory (skills/procedural) implicit or explicit?
Hanoi Tower What is an example of Nonasociative Learning?

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