chapter 25 and 26 Mul choice

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1) The mechanism that establishes the medullary osmotic gradient depends most on the permeability properties of the ________.
A) loop of Henle
B) glomerular filtration membrane
C) collecting duct
D) distal convoluted tubule

A) loop of Henle

2) Urine passes through the ________.
A) renal hilum to the bladder to the ureter
B) pelvis of the kidney to ureter to bladder to urethra
C) glomerulus to ureter to renal tubule
D) hilum to urethra to bladder

B) pelvis of the kidney to ureter to bladder to urethra

3) Which of the following is not associated with the renal corpuscle?
A) a podocyte
B) a vasa recta
C) a fenestrated capillary
D) an efferent arteriole

B) a vasa recta

4) An increase in the permeability of the cells of the collecting tubule to water is due to a(n) ________.
A) decrease in the production of ADH
B) increase in the production of ADH
C) increase in the production of aldosterone
D) decrease in the concentration of the blood plasma

B) increase in the production of ADH

5) The urinary bladder is composed of ________ epithelium.
A) transitional
B) simple squamous
C) stratified squamous
D) pseudostratified columnar

A) transitional

6) The kidneys are stimulated to produce renin ________.
A) when the peritubular capillaries are dilated
B) when the pH of the urine decreases
C) by a decrease in the blood pressure
D) when the specific gravity of urine rises above 1.10

C) by a decrease in the blood pressure

7) Which of the choices below is not a function of the urinary system?
A) helps maintain homeostasis by controlling the composition, volume, and pressure of blood
B) regulates blood glucose levels and produces hormones
C) maintains blood osmolarity
D) eliminates solid, undigested wastes and excretes carbon dioxide, water, salts, and heat

D) eliminates solid, undigested wastes and excretes carbon dioxide, water, salts, and heat

8) Which gland sits atop each kidney?
A) adrenal
B) thymus
C) pituitary
D) pancreas

A) adrenal

9) The ________ artery lies on the boundary between the cortex and medulla of the kidney.
A) lobar
B) arcuate
C) interlobar
D) cortical radiate

B) arcuate

10) The glomerulus differs from other capillaries in the body in that it ________.
A) has a basement membrane
B) is impermeable to most substances
C) is drained by an efferent arteriole
D) has a blood pressure much lower than other organ systems

C) is drained by an efferent arteriole

11) The descending limb of the loop of Henle ________.
A) is not permeable to water
B) is freely permeable to sodium and urea
C) pulls water by osmosis into the lumen of the tubule
D) contains fluid that becomes more concentrated as it moves down into the medulla

D) contains fluid that becomes more concentrated as it moves down into the medulla

12) Select the correct statement about the ureters.
A) Ureters contain sphincters at the entrance to the bladder to prevent the backflow of urine.
B) The epithelium is stratified squamous like the skin, which allows a great deal of stretch.
C) The ureters are capable of peristalsis like that of the gastrointestinal tract.
D) The ureter is innervated by parasympathetic nerve endings only.

C) The ureters are capable of peristalsis like that of the gastrointestinal tract.

13) The fatty tissue surrounding the kidneys is important because it ________.
A) ensures adequate energy for the adrenal glands to operate efficiently
B) stabilizes the position of the kidneys by holding them in their normal position
C) is necessary as a barrier between the adrenal glands and kidneys
D) produces vitamin D

B) stabilizes the position of the kidneys by holding them in their normal position

14) The renal corpuscle is made up
of ________.
A) Bowman's capsule and glomerulus
B) the descending loop of Henle
C) the renal pyramid
D) the renal papilla

A) Bowman's capsule and glomerulus

15) The functional and structural unit of the kidneys is the ________.
A) nephron
B) loop of Henle
C) glomerular capsule
D) basement membrane of the capillaries

A) nephron

16) The juxtaglomerular apparatus is responsible for ________.
A) the secretion of drugs
B) the secretion of acids and ammonia
C) reabsorption of organic molecules, vitamins, and water
D) regulating the rate of filtrate formation and controlling systemic blood pressure

D) regulating the rate of filtrate formation and controlling systemic blood pressure

17) The chief force pushing water and solutes out of the blood across the filtration membrane is ________.
A) the design and size of the podocytes
B) the thickness of the capillary endothelium
C) glomerular hydrostatic pressure (glomerular blood pressure)
D) the size of the pores in the basement membrane of the capillaries

C) glomerular hydrostatic pressure (glomerular blood pressure)

18) Which of the following statements describes the histology of the ureters?
A) They are trilayered (mucosa, muscularis, and adventitia).
B) They are actually an extension of the visceral peritoneum.
C) They are made up of several layers of endothelium.
D) They are made up entirely of muscle tissue because they need to contract in order to transport urine efficiently.

A) They are trilayered (mucosa, muscularis, and adventitia).

19) Which of the following statements is a false or incorrect statement?
A) The male urethra serves both the urinary and reproductive systems at the same time.
B) The male urethra serves both the urinary and reproductive systems but at different times.
C) The male urethra is longer than the female urethra.
D) The male urethra is a passageway for both urine and semen.

A) The male urethra serves both the urinary and reproductive systems at the same time.

20) Which of the following acts as the trigger for the initiation of micturition (voiding)?
A) the stretching of the bladder wall
B) motor neurons
C) the pressure of the fluid in the bladder
D) the sympathetic efferents

A) the stretching of the bladder wall

21) The filtration membrane includes all except ________.
A) glomerular endothelium
B) podocytes
C) renal fascia
D) basement membrane

C) renal fascia

22) The mechanism of water reabsorption by the renal tubules is ________.
A) active transport
B) osmosis
C) solvent drag
D) cotransport with sodium ions

B) osmosis

23) Most electrolyte reabsorption by the renal tubules is ________.
A) not Tm limited
B) in the distal convoluted tubule
C) hormonally controlled in distal tubule segments
D) completed by the time the loop of Henle is reached

C) hormonally controlled in distal tubule segments

24) The macula densa cells respond to ________.
A) aldosterone
B) antidiuretic hormone
C) changes in pressure in the tubule
D) changes in solute content of the filtrate

D) changes in solute content of the filtrate

25) Which of the following is not reabsorbed by the proximal convoluted tubule?
A) Na+
B) K+
C) glucose
D) creatinine

D) creatinine

26) The fluid in the glomerular (Bowman's) capsule is similar to plasma except that it does not contain a significant amount of ________.
A) glucose
B) hormones
C) electrolytes
D) plasma protein

D) plasma protein

27) Alcohol acts as a diuretic because it ________.
A) is not reabsorbed by the tubule cells
B) increases the rate of glomerular filtration
C) increases secretion of ADH
D) inhibits the release of ADH

D) inhibits the release of ADH

28) The function of angiotensin II is to ________.
A) constrict arterioles and increase blood pressure
B) decrease the production of aldosterone
C) decrease arterial blood pressure
D) decrease water absorption

A) constrict arterioles and increase blood pressure

29) A disease caused by inadequate secretion of antidiuretic hormone (ADH) by the pituitary gland with symptoms of polyuria is ________.
A) diabetes mellitus
B) diabetes insipidus
C) diabetic acidosis
D) coma

B) diabetes insipidus

30) An important characteristic of urine is its specific gravity or density, which is ________.
A) 1.041-1.073
B) 1.001-1.035
C) 1.030-1.040
D) 1.000-1.015

B) 1.001-1.035

31) Place the following in correct sequence from the formation of a drop of urine to its elimination from the body. 1. 2. 3. 4. 5. 6. major calyx minor calyx nephron urethra ureter collecting duct
A) 3, 1, 2, 6, 5, 4
B) 6, 3, 2, 1, 5, 4
C) 2, 1, 3, 6, 5, 4
D) 3, 6, 2, 1, 5, 4

D) 3, 6, 2, 1, 5, 4

32) Select the correct statement about the nephrons.
A) The parietal layer of the glomerular capsule is simple squamous epithelium.
B) The glomerulus is correctly described as the proximal end of the proximal convoluted tubule.
C) Podocytes are the branching epithelial cells that line the tubules of the nephron.
D) Filtration slits are the pores that give fenestrated capillaries their name.

A) The parietal layer of the glomerular capsule is simple squamous epithelium.

33) What would happen if the capsular hydrostatic pressure were increased above normal?
A) Net filtration would increase above normal.
B) Net filtration would decrease.
C) Filtration would increase in proportion to the increase in capsular pressure.
D) Capsular osmotic pressure would compensate so that filtration would not change.

B) Net filtration would decrease.

34) Which of the following is not a part of the juxtaglomerular apparatus?
A) granular cells
B) macula densa
C) podocyte cells
D) mesangial cells

C) podocyte cells

35) Tubular reabsorption ________.
A) includes substances such as creatinine
B) by active mechanisms usually involves movement against an electrical and/or chemical gradient
C) by passive processes requires ATP to move solutes from the interior of the tubule to the blood
D) is a way for the body to get rid of unwanted waste

B) by active mechanisms usually involves movement against an electrical and/or chemical gradient

36) Which of the following is not a reason why substances are either not reabsorbed or are incompletely reabsorbed from the nephron?
A) They lack carriers.
B) They are not lipid soluble.
C) They are too large to pass through the fenestrations.
D) They are extremely complex molecules.

D) They are extremely complex molecules.

37) Reabsorption of high levels of and glucose amino acids in the filtrate is accomplished by ________.
A) facilitated diffusion
B) passive transport
C) countertransport
D) secondary active transport

D) secondary active transport

38) Which of the choices below is a function of the loop of Henle?
A) form a large volume of very concentrated urine or a small volume of very dilute urine
B) form a large volume of very dilute urine or a small volume of very concentrated urine
C) absorb electrolytes actively with an automatic absorption of water by osmosis
D) none of these

B) form a large volume of very dilute urine or a small volume of very concentrated urine

39) Fetal kidneys do not have to work very hard because ________.
A) fetuses do not have any waste to excrete
B) there are no functional nephrons until after birth
C) the placenta allows the mother's urinary system to clear the waste from fetal blood
D) there is no way a fetus could excrete urine until the seventh month of development

C) the placenta allows the mother's urinary system to clear the waste from
fetal blood

40) Which of the following best describes kidney function in older adults (70 years or older)?
A) Kidney function remains the same throughout life, regardless of age.
B) Only about 3% of older adults have any loss of kidney function.
C) Only obese and diabetic older adults have any kidney dysfunction.
D) Kidney function decreases due to kidney atrophy.

D) Kidney function decreases due to kidney atrophy.

41) The factor favoring filtrate formation at the glomerulus is the ________.
A) colloid osmotic pressure of the blood
B) glomerular hydrostatic pressure
C) capsular hydrostatic pressure
D) myogenic mechanism

B) glomerular hydrostatic pressure

42) If the Tm for a particular amino acid is 120 mg/100 ml and the concentration of that amino acid in the blood is 230 mg/100 ml, the amino acid will ________.
A) be actively secreted into the filtrate
B) be completely reabsorbed by the tubule cells
C) appear in the urine
D) be reabsorbed by secondary active transport

C) appear in the urine

43) If one says that the clearance value of glucose is zero, what does this mean?
A) The glucose molecule is too large to be filtered out of the blood.
B) Most of the glucose is filtered out of the blood and is not reabsorbed in the convoluted tubules.
C) Normally all the glucose is reabsorbed.
D) The clearance value of glucose is relatively high in a healthy adult.

C) Normally all the glucose is reabsorbed.

44) Excretion of dilute urine requires ________.
A) relative permeability of the distal tubule to water
B) impermeability of the collecting tubule to water
C) transport of sodium and chloride ions out of the descending loop of Henle
D) the presence of ADH

B) impermeability of the collecting tubule to water

45) Which of the choices below is not a method by which the cells of the renal tubules can raise blood pH?
A) by secreting hydrogen ions into the filtrate
B) by reabsorbing filtered bicarbonate ions
C) by producing new bicarbonate ions
D) by secreting sodium ions

D) by secreting sodium ions

46) In the ascending limb of the loop of Henle the ________.
A) thin segment is freely permeable to water
B) thick segment is permeable to water
C) thin segment is not permeable to sodium and chloride
D) thick segment moves ions out into interstitial spaces for reabsorption

D) thick segment moves ions out into interstitial spaces for reabsorption

47) Select the correct statement about urinary system development.
A) Kidneys develop from urogenital ridges.
B) The metanephric ducts will become the urethras.
C) The pronephros (first tubule system) develops during the tenth week of gestation.
D) The mesonephros will develop into the kidneys.

A) Kidneys develop from urogenital ridges.

48) Which of the choices below does not describe the importance of tubular secretion?
A) disposing of substances not already in the filtrate, such as certain drugs
B) eliminating undesirable substances such as urea and uric acid that have been reabsorbed by passive processes
C) ridding the body of bicarbonate ions
D) ridding the body of excessive potassium ions

C) ridding the body of bicarbonate ions

49) Which statement is correct?
A) Reabsorption of water is hormonally controlled.
B) Normal filtrate contains a large amount of protein.
C) Most of the water passing through the kidney is eliminated as urine.
D) The excretion of sodium ions is one of the mechanisms that maintains the pH balance of the blood.

A) Reabsorption of water is hormonally controlled.

50) What is the function of the juxtaglomerular apparatus?
A) help regulate blood pressure and the rate of blood filtration by the kidneys
B) help regulate blood pressure and the rate of excretion by the kidneys
C) help regulate urea absorption by the kidneys
D) help regulate water and electrolyte excretion by the kidneys

A) help regulate blood pressure and the rate of blood filtration by the kidneys

51) Which of the choices below is the salt level-monitoring part of the nephron?
A) macula densa
B) principal cell
C) vasa recta
D) loop of Henle

A) macula densa

52) Which of the hormones below is responsible for facultative water reabsorption?
A) ADH
B) thyroxine
C) aldosterone
D) atrial natriuretic peptide

A) ADH

53) Which of the choices below is not a glomerular filtration rate control method?
A) renal autoregulation
B) neural regulation
C) electrolyte levels
D) hormonal regulation

C) electrolyte levels

54) Which of the choices below are the most important hormone regulators of electrolyte reabsorption and secretion?
A) angiotensin II and ADH
B) angiotensin II and aldosterone
C) angiotensin I and epinephrine
D) angiotensin I and atrial natriuretic peptide

B) angiotensin II and aldosterone

55) Which cells of the kidney are chemoreceptors that respond to changes in solute content of the filtrate?
A) juxtaglomerular cells
B) mesangial cells
C) macula densa cells
D) podocytes

C) macula densa cells

93) The body's water volume is closely tied to the level of which of the following ions?
Ref: 1002-1004
A) calcium ions
B) potassium ions
C) hydrogen ions
D) sodium ions

D) sodium ions

94) Which of the follwing hormones is important in the regulation of sodium ion concentrations in the extracellular fluid?
Ref: 1004
A) antidiurectic hormone
B) erythropoietin
C) aldosterone
D) renin

C) aldosterone

95) Which of the following two organs function as the most important physiological buffer systems?
Ref: 1010-1011
A) the lungs and the kidneys
B) the adrenal glands and the testes
C) the thyroid gland and the heart
D) the stomach and the liver

A) the lungs and the kidneys

96) The fluid link between the external and internal environment is ________.

plasma

97) Whereas sodium is found mainly
in the extracellular fluid, most ________ is found in the intracellular fluid.
Ref: 997; Fig. 26.2
A) iron
B) chloride
C) potassium
D) magnesium

C) potassium

98) Which of the following describes the distribution of sodium and potassium between cells and body fluids?

Ref: 997; Fig. 26.2
A) K+ mainly in the cells, Na+ in the body fluids
B) Na+ mainly in the cells, K+ in the body fluids
C)equal amounts of each iron in the cells and body fluids
D) little of either in cells, but large amounts of each in body fluids

A) K+ mainly in the cells, Na+ in the body fluids

99) A falling blood pH and a rising partial pressure of carbon dioxide due to pneumonia or emphysema indicates ________.
Ref: 1014; Tbl. 26.2
A) respiratory acidosis
B) respiratory alkalosis
C) metabolic acidosis
D) metabolic alkalosis

A) respiratory acidosis

100) The maintenance of the prope
r pH of the body fluids may be the result of ________.
a) the control of the respiratory ventilation
b) the operation of the various buffer systems in the stomach
c) the active secretion of OH- into the filtrate by the kidney tubule cells
d) control of the acids produced in the stomach

A) the control of the respiratory ventilation

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