5 Written questions
5 Matching questions
- How do you tx Giant Cell Arteritis?
- What is the tx for ITP?
- How do you treat polyarteritis nodosa?
- What has lab findings of anemia, mild leukocytosis, elevated ESR, hilar adenopathy, C-ANCA (limited to kidney) and P-ANCA (localized to kidney)?
- What should you screen for in pt's with polyarteritis nodosa?
- a urgently with prednisone 60 mg/d immediately -> bx to confirm/ then low dose ASA 81 mg/d/ continue prednisone 1 month before tapering
- b Hep screening since 10% associated with Hep B
- c Wegener's Granulomatosis
- d high dose corticosteroids (60 mg Prednisone daily), Methylprednisolone 1 g IV daily for 3 days if critically ill, immunosuppressive agents like Cyclophosphamide; Hep B responds to short course of prednisone + lamivudine 100 mg/d and plasmapheresis 3 wk for 6 weeks
- e PISD = initial tx: Prednisone 1-2 mg/kg/day; high dose IV Ig of 1 g/kg for 1-2 days for platelet counts < 5000; Splenectomy is definitive tx; Danazol 600 mg/day if all of above fail
5 Multiple choice questions
- High dose prednisone 40-60 mg/d tapered slowly after 1 month; immunosuppressive agents
- Polyarteritis Nodosa; poor prognosis
- Polyarteritis Nodosa
- Giant Cell Arteritis
5 True/False questions
How do you tx Wegener's Granulomatosis? → angiography
What are the different types of systemic vasculitis? → hematologic malignancies, aplastic anemia
A pt comes in with purpura, petechiae and hemorrhagic bullae in their mouth. What do they have? → Myasthenia Gravis (chronic autoimmune neuromuscular disorder with varying degrees of weakness of skeletal (voluntary) muscles of body)/ mya - muscles, anticholinesterase, acetylcholine receptor antibodies
What is tx for Takayasu's arteritis? → angiography
What is the hallmark in lab findings for ITP? → hematologic malignancies, aplastic anemia