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5 Written Questions

5 Matching Questions

  1. What is a group of vascular dz's that cause inflammatory injury and necrosis of the blood vessels? They are classified as small, medium or large.
  2. What is tx for Takayasu's arteritis?
  3. What is a rare disorder with vasculitis of small arteries and symptoms of nasal congestion, sinusitis and otitis media as well as fever, cough, dyspnea, wt loss and malaise? It is in males or females in their 4th-5th decades
  4. What should you screen for in pt's with polyarteritis nodosa?
  5. What is the hallmark in lab findings for ITP?
  1. a Systemic Vasculitis
  2. b P M & M: Prednisone 1 mg/kg/d tapered to < 20 in 8-20 wks with maintenance at 10 mg; Methotrexate 25 mg/wk and mycophenolate mofetil 1500 mg bid for those who are refractory
  3. c Wegener's Granulomatosis (fatal if not treated)
  4. d Hep screening since 10% associated with Hep B
  5. e thrombocytopenia with platelet counts less than 10,000/mcL (counts less than 5000/mcL can lead to CNS bleeding); peripheral smear, bone marrow and coagulation studies are normal

5 Multiple Choice Questions

  1. Polyarteritis Nodosa; poor prognosis
  2. idiopathic thrombocytopenia purpura (ITP); chief complaint - mucosal or skin bleeding
  3. PE MEAT: Paranasal sinus abnormalities, Eosinophilia > 10% on diff, Mononeuropathy, Extravascular eosinophils positive biopsy, Asthma, Transient pulmonary infiltrates
  4. High dose prednisone 40-60 mg/d tapered slowly after 1 month; immunosuppressive agents
  5. hematologic malignancies, aplastic anemia

5 True/False Questions

  1. What is a vasculitis that presents in pts over 50 with a warning headache, visual symptoms, jaw claudication, throat pain, dry cough, and a fever? It affects medium and large arteries. There is an asymmetry of pulses in arms, murmur of aortic regurgitation and bruits near the clavicle.Giant Cell Arteritis


  2. What are the different types of systemic vasculitis?hematologic malignancies, aplastic anemia


  3. For ITP you are asymptomatic till you start bleeding at...? What is your prognosis?nose, soft palate, petechiae, gums, GI and CNS; good


  4. What Ig is involved with ITP? Which cell lines are affected?autoimmune do where IgG antibody formed that binds to platelets; destruction in spleen; isolated thrombocytopenia (other cell lines normal)


  5. What is apulseless disease or pulse discrepance btwn extremities of > 30 mm Hg, aortic arch syndrome, young female arteritis of Asian descent? It affects large vessels and also are symptoms of fever, dizziness, fainting, stroke and night sweats.Takayasu's Arteritis


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