Intro to immune system
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22 terms
Terms | Definitions |
|---|---|
 What are the three unique features of the immune system? DEFINE EACH | recognition-self from non self, specificity-response directed against specific stimulus, learning&memory-response improves with repeat exposure |
| what is the function of the thymus? | act on bone marrow stems cells to produce T cells |
| in birds/chickens what is the function of the bursa? | acts on stem cells to produce immunologically competent B cells |
| what is the human equivalent of a bursa? | ???,B cells mature in fetal liver and in the bone marrow after birth |
| how does the t cell interact with an antigen? | through a TCR (t cell receptor) |
| what are the two pan T cell markers? | CD3 and CD2 |
| what is the function of CD3 and CD2 | they are pan T-cell markers |
| what marker does a Th(T helper) cell have? | CD4 |
| what marker does a Tc (T cytotoxic) cell have? | CD8 |
| class I major histone compatibility marker is found on what proportion of t cells? | All of them |
| class II major histone compatibility marker is found on what proportion of t cells? | some ACTIVATED T cells |
| what is the purpose of the membrane immuno globulin marker? | antigen specific receptor that delivers signal to B cell |
| what is the purpose of the Fc receptor marker? | receptor for Fc of IgG that delivers signal to b cell |
| tissue rejection: cell mediated or antibody mediated? | cell mediated |
| delayed hypersensitivity: cell mediated or antibody mediated? | cell mediated |
| graft vs. host rx: cell mediated or antibody mediated? | cell mediated |
| agglutination: cell mediated or antibody mediated? | effector molecules |
| toxic neutralization: cell mediated or antibody mediated? | effector molecules |
| immediate hypersensitivity: cell mediated or antibody mediated? | effector molecules |
| primary lymphoid follicle layer breakdown | center: dividing b cells |
| secondary lymphoid follicle layer breakdown | center: dividing b cells and plasma cells mantle: b cells and some t cells |
| secondary follicle of the spleen layer breakdown | germinal center:rapidly dividing b cells and plasma cells mantle: b cells sheath: t cells marginal zone: antigen presenting cells |
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