Antibiotics
About this set
Created by:
lukeburleson1 on August 10, 2011
Subjects:
Log in to favorite or report as inappropriate.
Order by
26 terms
Terms | Definitions |
|---|---|
 Quinolones | Bind DNA gyrase or topoisomerase |
| Sulfas and trimethoprim | Inhibits DHPT synth and DHFR to inhibit folate synth |
| Chloramphenicol | Binds 50S subunit to inhibit peptidyl transfer |
| Rifampin | Binds DNA-directed RNA polymerase to inhibit mRNA synth |
| Linezolid | Bind peptidyl-transferase center on 23S RNA Blocks fMet-tRNA and initiation |
| Aminoglycosides | Bind 30S subunit to cause misreads and leaky membrane |
| Vancomycin | Binds D-ala-Dala of peptidoglcyan to prevent cross-linking |
| Retapamulin | Binds 50S subunit and inhibits Rb peptidyl transferase |
| B-lactams | Bind PBPs to prevent cell-wall cross-links |
| Anti-sense RNA | Blocks translation of CMV mRNA |
| Tetracyclines | Bind 30S subunit to block acceptor site and inhibit AA-tRNA binding |
| Daptomycin Polymyxin | Ca2+ dependent insertion into membrane and depolarization |
| Imidazoles | Antifungals that inhibit ergesterol synth CYP450 inhibitors |
| IFN gamma | Blocks transcription and translation by protein kinase inhibiting eIF-2 and RNase |
| Clindamycin | Bind 50s subunit Inhibits peptidyl transferase |
| Disoxaril | Blocks uncoating of picornaviruses by blocking receptor-binding cleft |
| Amphotericin B | Anti-fungal polyene Disrupts fungal cell membrane by binding ergesterol |
| Caspofungin | Block cell wall synth by inhibiting B-glycan polysaccharide synth |
| Nucleotide analogs | Block viral DNA replication by inhibiting DNA polymerase and chain elongation Majority of anti-virals |
| Mupirocin | Binds bacterial iso-leucyl-tRNA synthetase Inhibits protein synth |
| Amantidine Rimantidine | Uncoating of flu A by blocking viral ion channel |
| Protease inhibitors | Prevent viral polyprotein cleavage and assembly Tx HIV |
| Relenza Tamiflu | Inhibits flu A and B neuramidase and virus release |
| Macrolids | Bind reversibly to 50S dissociating tRNA and terminating peptide |
| Streptogramins (Synercid) | Inhibit protein synth Bind to peptidyl transferase and tRNA synthetase |
| Ribavirin | Inhibit nucleotide biosynth, mRNA cap formation and RNA polymerase |
First Time Here?
Welcome to Quizlet, a fun, free place to study. Try these flashcards, find others to study, or make your own.