| Term | Definition |
|---|
| The chemical classification of morphine is | opiate |
| The physiologic classification of morphine is | CNS depressant |
| Theraputic classification of morphine is | analgesic |
| After meals | pc |
| before meals | ac |
| chemical name | atomic/molecular name |
| generic name | off brand |
| Side effect | usually mild to moderate & may be transient. It is somewhat expected |
| Paradoxical effect | unique response, usually the opposite of intended effect |
| Idiosyncratic | unusual, unexpected |
| Adverse effects | All non-theraputic responses, unintended, to the normal dose. May be uncomfortable, annoying, to awful. |
| Schedule I | heroin - no medical use, high abuse & dependance potential |
| Schedule II | pot - high abuse & dependence but with some medicinal use |
| Schedule III | vikaden, anabolics - moderate abuse/dependancy, more medical uses |
| Schedule IV | low risk with medical use |
| Lowest risk | some available without prescription |
| Controlled substances are substances that are: | strictly monitored |
| 1906 Food & drug act | When you could no longer prescribe an Rx without good reason, federal law regulated taxed ..... |
| 1938 food, drug, & cosmetic act | protects us from mislabeled or use of drugs |
| Kefauver-Harris Amendment in the early 1960's | had to provide proof of the drug's safety & efficacy, came about due to the thalidomide tragedies |
| harrison narcotic act 1914 | import & export of opiates |
| 1970 comprehensive drug abuse prevention & control act | required to maintain physical security & good records of drug distribution |
| Pharmacodynamics | How the drug affects the body |
| Pharmacokinetics, often referred to as ADME | the effect the body has on the drug |
| Metabolism most often takes place in the: | liver |
| Excretion most often takes place in the: | kidney |
| How long does it take a drug to go through the four phases of clinical trials? | 5-9 years |
| Phase I is 20 - 80 healthy volunteers, Phase II is ________________patients with the targeted problem, Phase III is 1000 - 3000 patients with the targeted problem (gold standard comparison), & phase IV is___________________. | 100 - 300, surveilance of safety & ongoing targets |
| twice a day | bid |
| three times a day | tid |
| four times a day | qid |
| as needed | prn |
| by mouth | po |
| The 5 R's | rights to passing meds - right patient, drug, time, dose, & route |
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