NAME

Question types


Start with


Question limit

of 30 available terms

Advertisement Upgrade to remove ads
Print test

5 Written questions

5 Matching questions

  1. Coccidioides immitis Immunity
  2. Coccidioides immitis Morphology
  3. Blastomyces dermatitidis Pathogenesis
  4. Coccidioides immitis Reservoir
  5. Blastomyces dermatitidis Reservoir
  1. a Dimorphic
    1. Mycelial forms with spores at 25 C
    2. Yeast forms at 37 C
  2. b 1. Desert areas of the southwestern US & northern Mexico
    2. Respiratory transmission
  3. c 1. Primary infection is by inhalation of the conidia
    2. A mixed inflammatory response occurs
    3. The organism then starts to grow as large yeasts with thick double walls
    4. Unlike Histoplasma, these yeasts are extracellular and much larger
  4. d 1. Mississippi river valley extending north to the great lakes
    2. Resides in soil or rotten wood
    3. Respiratory transmission
  5. e 1. Life long immunity does develop
    2. Conidia can be phagocytosed and killed by PMNs
    3. The endospores cannot be handled until macrophages are activated by T-cells (Th1)
    4. Humoral immunity does not play a role
    5. Complement is not effective at opsonizing C. immitis

5 Multiple choice questions

  1. 1. Itraconazole
    2. Amphotericin B (in immunocompromised patients)
  2. 1. trimethoprim/sulfamethoxazole (TMP sulfa): 1st choice
    2. itraconazole and amphotericin B
  3. 1. Not clear what the predominant host response is
    2. Complement, antibody and cell mediated immunity are all involved
  4. 1. fevers, sweats, weight loss
    2. in disseminated disease, skin & subcutaneous nodules and mucous membrane ulcerations are not unusual (tongue, larynx)
  5. 1. Central and S. America
    2. Brazil

5 True/False questions

  1. Blastomyces dermatitidis Treatment1. Not clear what the predominant host response is
    2. Complement, antibody and cell mediated immunity are all involved

          

  2. Paracoccidioides brasiliensis Clinical Symptoms1. Pulmonary Infection
    2. Cough
    3. Fever
    4. Malaise
    5. Weight loss

          

  3. Histoplasma capsilatum Immunity1. The main control of this organism is by cell mediated immunity
    -Mainly the T-cell activation of macrophages

    2. Neither B cells or antibody have a significant role

          

  4. Bastomyces dermatitidis Morphology1. Mycelial forms with spores at 25 C
    2. Yeast forms at 37 C

          

  5. Coccidiodes immitis Diagnosis1. Biopsy of affected tissue: lung, skin
    A. Silver stain or KOH prep
    B. Culture on Sabouraud's agar (warn lab!) 3-4 days
    2. Serology
    3. Skin tests (tests for exposire only)

          

Create Set