| Term | Definition |
|---|
| Penicillin G | Regular penicillin, not V, given oral or IV |
| Penicillin V | Regular penicillin, not G, given oral |
| Oxacillin | Antistaph penicillin, used for hepatitis |
| Nafcillin | Antistaph penicillin, expelled by Salmonella via an efflux pump |
| Methicillin | Antistaph penicillin, used for interstitial nephritis, staph can become resistant by modification of PBP |
| Ampicillin | Extended spectrum penicillin, sometimes used with sulbactam |
| Amoxicillin | Extended spectrum penicillin, sometimes used with clavulanate |
| Piperacillin | Extended spectrum IV penicillin, sometimes used with tazobactam |
| Ticarcillin | Extended spectrum penicillin |
| Cephalexin | 1st generation cephalosporin, most active against gram positive cocci, with limited activity against gram negatives, used for GAS and S. aureus cellulitis |
| Cefazolin | 1st generation cephalosporin, most active against gram positive cocci, with limited activity against gram negatives |
| Cefoxitin | 2nd generation cephalosporin, used for intraabdominal infections, not cefotetan |
| Cefotetan | 2nd generation cephalosporin, used for intraabdominal infections, not cefoxitin |
| Cefuroxime | 2nd generation cephalosporin, less active against gram positives than 1st generation, but extended gram negative coverage |
| Ceftriaxone | 3rd generation cephalosporin, increased activity against gram negatives not covered by 1st or 2nd generation, distribution across BBB |
| Ceftazidime | 3rd generation cephalosporin, used for Pseudomonas aeruginosa |
| Cefepime | 4th generation cephalosporin, good penetration into CSF, used for sepsis, MDR gram negatives |
| Sulbactam | Used with ampicillin as a beta lactamase inhibitor |
| Tazobactam | Used with piperacillin as a beta lactamase inhibitor |
| Imipenem | Carbapenem, broad spectrum against gram negatives, gram positives, and anaerobes, wide distribution including CSF, renally cleared |
| Meropenem | Carbapenem similar to imipenem |
| Aztreonam | Monobactam, useful for penicillin allergic patients, resistant to beta lactamases, good activity against gram negatives, no activity against gram positives or anaerobes |
| Vancomycin | Inhibits cell wall synthesis, binds D-Ala-D-Ala terminus of peptidoglycan, only active against gram positives |
| Daptomycin | Binds cytoplasmic membrane via calcium, causing rapid depolarization and cell death, only active against gram positives |
Combine with other sets
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