the (8) mechanisms of vascular disease

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emw2eq  on September 10, 2011

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the (8) mechanisms of vascular disease

hemorrhage
violation of the normal blood vessel allowing for escape of blood out of vascular space
1. extra vascular course
2. decreased integrity of vascular wall itself
3. clotting disorders
(*scurvy: main cause of death was hemorrhage because vit. c is needed to maintain integrity of blood vessels)
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hemorrhage violation of the normal blood vessel allowing for escape of blood out of vascular space
1. extra vascular course
2. decreased integrity of vascular wall itself
3. clotting disorders
(*scurvy: main cause of death was hemorrhage because vit. c is needed to maintain integrity of blood vessels)
thrombosis clotting in a blood vessel
arterial or venous
major mechanism of stroke, heart attack
(complete occlusion of a vessel by a clot in one place)
(always refers to platelets)
embolism clots travel in blood vessels --> clot travels from far away to closer to the tissue
(thrombosis that breaks off and travels distally)
-traveling clots, air embolisms (management of IVs), fat embolism (broken bones, fatty marrow)
hyperplasia very thick wall of blood vessel; cause can be hypertension
stenosis: narrowing of the blood vessel
hyperplastic disorder
inflammation is a mechanism of vascular disease: vasculitis
-phlebitis:in a vein
-arteritis: in an artery
spasm cocaine: causes spasms especially IV form, leads to HA
prinzmetal angina: strictly a spasm problem, can be prevented, manifestation of stress, blood vessels spasm causing HA
raynaud's disease: digital spasms
dilation migraine headaches (dilation of arteries, meingeal)
shock - BP drop, vascular compartment expands
vericose veins: dilated veins
degeneration angiodysplasia: abnormal growth in a blood vessel = most common cause of rectal bleeding
*scurvy leads to degenerative disease of blood vessels
endpoints of mechanism, vascular disease leads to:
A.
A.) excessive flow/volume
-causes:
(1)edema - leaking of blood into interstitial space (pitting edema: push and leave a dimple, early sign of heart failure)
(2) effusions: fluid in a body cavity
-can get into air spaces in the body
-consequene of too much blood
endpoints of mechanism, vascular disease leads to:
B.
B.) inadequate flow/volume
partial = ischemia
complete = infarction, complete cessation of blood flwo

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emw2eq