Perio Chapter 5 Study Guide & Chapter Questions

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Created by:

JHuguelet  on September 11, 2011

Subjects:

dental-hygiene

Description:

Microbiology of Periodontal Disease

Classes:

perio II, Periodontology II

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Perio Chapter 5 Study Guide & Chapter Questions

Bacteria
microorganisms composed of a single cell than only can be seen through a microscope
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Terms

Definitions

Bacteria microorganisms composed of a single cell than only can be seen through a microscope
Innocuous not harmful; innocent
Pathogenic capable of causing disease in human beings
Gram-positive bacteria bacteria with a thick, single cell wall that retains a purple color when stained with a dye known as crystal violet
Gram-negative bacteria bacteria with double cell walls that do not stain a purple color when stained with a dye known as crystal violet; believed to play an important role in the tissue destruction seen in periodontitis
Aerobic bacteria bacteria that require oxygen to live
Anaerobic bacteria bacteria that cannot live in the presence of oxygen
Facultative anaerobic bacteria bacteria that can exist either with or without oxygen
Biofilm a well-organized community of bacteria that adheres to surfaces and is embedded in an extracellular slime layer. Form rapidly on any wet surface and usually consist of many species of bacteria as well as other organisms and debris
Extracellular slime layer a protective barrier that surrounds the mushroom-shaped bacterial microcolonies of a biofilm; protects the bacterial microcolonies from antibiotics, antimicrobials, and host defense mechanisms
Bacterial plaque a biofilm that adheres tenaciously to tooth surfaces, restorations, and prosthetic appliances
Fimbriae hairlike structures that bacteria use to connect to the pellicle and each other
Pellicle thin coating of salivary proteins that attach to the tooth surface
Bacterial blooms periods when specific species or groups of species grow at rapidly accelerated rates within the dental plaque biofilm
Mixed infection an infection caused by and associated with multiple bacteria
Actinobacillus actinomycetemcomitans a gram-negative bacterium that has been identified as an etiologic agent of periodontitis (Aa)
Bacteroides forsythus a gram-negative bacterium that has been identified as an etiologic agent of periodontitis; former name of Tf
Tannerella forsythensis a gram-negative bacterium that has been identified as an etiologic agent of periodontitis; new name of Bf
Fusobacterium nucleatum gram-negative nonmotile bacteria found in the early stages of gingivitis and is a prominent component of the subgingival plaque in perio with severe attachment loss; early inflammatory changes in tissue (Fn)
Porphyromonas gingivalis a gram-negative bacterium that has been identified as an etiologic agent of periodontitis (Pg)
Tooth-attached plaque a type of plaque found within a periodontal pocket that is attached to the tooth surface
Unattached plaque a type of plaque found within a periodontal pocket that is not attached to either the tooth surface or the epithelium of the pocket wall
Virulence factors mechanisms that enable biofilm bacteria to colonize, invade, and damage the tissues of the periodontium; may be structural characteristics of the bacterium itself or substances produced and released into the environment by bacteria
Virulent ability to cause disease
Lipopolysaccharide (LPS) a major component of the cell walls of gram-negative bacteria that will initiate the host immune response; also known as cellular endotoxin
Exotoxins harmful proteins released from the bacterial cell that act on host cells at a distance
Endotoxins a major component of the cell wall of gram-negative bacteria that will initiate the host immune response; also known as LPS
Bacterial enzymes cytotoxic agents that are harmful or destructive to host cells
Herpes virus (HSV) associated with Chronic perio, Aggressive perio, NUG, HIV perio, Gingival recession, Perio associated with systemic conditions
Human cytomegalovirus (HCMV) associated with Chronic perio, Aggressive perio, NUG, HIV perio, Gingival recession, Perio associated with systemic conditions
Importance of attached bacteria in the development of periodontal diseases inner layers are dominated by gram +, but gram (-) are also present
Methods for successful removal of biofilm mechanical
Bacterial virulence factors ability to invade tissues
LPS cause tissue destruction
exotoxins cause leukocyte destruction
enzymes assist in tissue invasion
Bacteria associated with dental caries Lactobacillus, Streptococcus mutans, Streptococcus sobrinus
Bacteria associated with periodontal disease Aa, Fn, Pg, Bf, Streptococcus intermedius, campylobacter rectus, Eubacterium nodatum, Prevotella intermedia, Peptostretococcus micros, Prevotella nigrescens, Treponema denticola
Prevotella intermedia gram-negative obligate anaerobic rod associated with pregnancy gingivitis and NUP; moderate etiology
Treponema denticola gram-negative anaerobic spirochete associated with chronic perio, NUP; moderate (book) to strong (others) etiology
Capnocytophaga gram-negative facultative rod associated with aggressive localized perio; moderate etiology
Bacterial color complex classification closer to red the color, more pathogenic it is
Theory of HSV association with periodontal disease infects neutrophils, macrophages, T & B lymphocytes; infect & lyse fibroblasts; lead to an upregulation of TNF & IL-1
Theory of HCMV association with periodontal disease infect & lyse fibroblasts; lead to an upregulation of TNF & IL-1
bacterium a single microscopic organism is termed:
Gram-negative bacteria that have double cell walls and that do not stain purple with crystal violet are called:
biofilm a well-organized community of bacteria that adheres to surfaces and is embedded in an extracellular slime layer is termed:
extracellular slime layer which structure of a biofilm protects the bacterial microcolonies from systemic antibiotics and the body's immune system?
fluid channels which structure of a biofilm facilitates the movement of nutrients to the bacteria?
toothbrush and floss what would be most effective in controlling the bacteria in a dental plaque biofilm?
a toothbrush and floss cannot clean root surfaces within a periodontal pocket why is frequent periodontal instrumentation important in the control of dental plaque biofilms located in periodontal pockets?
actinobacillus actinomycetemcomitans which bacterium can be transmitted from one family member to another?

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